Estrogen Deficiency Alters Vascularization and Mineralization Dynamics: Insight from a Novel 3-D Humanized and Vascularized Bone Organoid Model

The Impact of Estrogen Deficiency on Vascularization and Mineralization Dynamics—Insights from a Novel 3D Humanized and Vascularized Bone Organoid Model Academic Background Osteoporosis is a common bone disease, particularly prevalent among postmenopausal women. Osteoporosis not only manifests as a reduction in bone mass but also involves changes i...

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

Academic Report on “Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss” Background Muscle tissues constitute a significant portion of human cellular mass and are a complex, highly vascularized, and dynamic tissue. However, traumatic or surgical Volumetric Muscle Loss (VML)—defined as the loss o...

Temporal and Spatial Regulation of Biomimetic Vascularization in 3D-Printed Skeletal Muscles

Temporal and Spatial Regulation of Biomimetic Vascularization in 3D-Printed Skeletal Muscles

Application of 3D Printing Technology in Skeletal Muscle Vascularization Research Academic Background Skeletal muscle tissue is one of the most important tissues in the human body, and its function relies on the close relationship between myotubes and the vascular network. The vascular network not only supplies oxygen and nutrients to skeletal musc...

Progress in Biomaterials-Enhanced Vascularization by Modulating Physical Properties

Research on the Modulation of Physical Properties of Biomaterials to Enhance Vascularization Background Introduction In the fields of tissue engineering and regenerative medicine, the formation of a vascular system and adequate blood perfusion are crucial for ensuring the supply of nutrients and oxygen within biomaterials. However, existing biomate...