Electroacupuncture Ameliorated Locomotor Symptoms in MPTP-Induced Mice Model of Parkinson’s Disease by Regulating Autophagy via Nrf2 Signaling

Medicine, Neurology,
Electroacupuncture   Autophagy   Nrf2 signaling   Parkinson’s disease   Neuroprotection   Motor function  

Study on Electroacupuncture Improving Parkinson’s Disease Symptoms by Regulating Autophagy Academic Background Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, primarily characterized by the gradual loss of dopamine (DA) neurons in the substantia nigra of the midbrain and the abnormal accumulation of α-synucle...

Histone Demethylases in Autophagy and Inflammation

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
Histone Demethylases   Autophagy   Inflammation   Epigenetics   Cell Signaling  

The Role of Histone Demethylases in Autophagy and Inflammation Background Introduction Autophagy is an essential lysosomal degradation process in eukaryotic cells, playing a critical role in cellular component renewal and homeostasis maintenance. Dysregulation of autophagy is associated with various diseases, including cancer, inflammatory diseases...

Microglial AKAP8L: A Key Mediator in Diabetes-Associated Cognitive Impairment via Autophagy Inhibition and Neuroinflammation Triggering

Medicine, Rheumatology and Immunology, Neurology, Life Sciences, Immunology,
AKAP8L   mTOR   Diabetes-Associated Cognitive Impairment   Microglia   Autophagy   Neuroinflammation  

Key Mediator Akap8l in Microglia for Diabetes-Associated Cognitive Impairment: Functions via Autophagy Inhibition and Neuroinflammation Academic Background In recent years, diabetes-associated cognitive impairment (DACI) has received increasing attention. It not only poses a threat to the self-management capabilities of diabetic patients but also i...