METTL14 Promotes Ferroptosis in Smooth Muscle Cells During Thoracic Aortic Aneurysm by Stabilizing the m6A Modification of ACSL4

Medicine, Cardiovascular System, Life Sciences, Cell Biology, Immunology,
ferroptosis   thoracic aortic aneurysm   smooth muscle cells   METTL14   ACSL4   m6A modification  

Mettl14 Promotes Ferroptosis in Vascular Smooth Muscle Cells During Thoracic Aortic Aneurysm by Stabilizing the m6A Modification of ACSL4 Academic Background Thoracic aortic aneurysm (TAA) is a severe vascular disease that often leads to aortic rupture and acute dissection, with extremely high mortality rates. Currently, the primary treatment for T...

m6A mRNA Methylation in Brown Fat Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis Independent of UCP1

Medicine, Endocrinology, Life Sciences, Cell Biology, Biochemistry,
brown fat   m6A methylation   insulin sensitivity   prostaglandin   lipid metabolism   METTL14   signaling  

The Role of m6A mRNA Methylation in Adipose Tissue: A Breakthrough Discovery of Cross-Organ Prostaglandin Signaling Axis in Insulin Sensitivity Regulation Research Background and Motivation In recent years, the potential role of brown adipose tissue (BAT) in human metabolic regulation has attracted widespread attention. Known for its thermogenic pr...