Obesity Intensifies Sex-specific Interferon Signaling to Selectively Worsen Central Nervous System Autoimmunity in Females

Obesity Intensifies Sex-specific Interferon Signaling to Selectively Worsen Central Nervous System Autoimmunity in Females

Medicine, Rheumatology and Immunology, Neurology, Life Sciences, Biochemistry, Immunology,
obesity   interferon signaling   sex differences   autoimmunity   central nervous system   multiple sclerosis  

Obesity Aggravates Female Central Nervous System Autoimmune Diseases Through Sex-Specific Interferon Signaling In recent years, the rising incidence of central nervous system (CNS) autoimmune diseases in females has garnered widespread attention. Obesity, as a potential environmental risk factor, has gradually become a research hotspot. The latest ...

Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity

Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity

Medicine, Rheumatology and Immunology, Basic Medical Sciences, Life Sciences, Immunology,
single-cell analysis   CAR T cell therapy   central nervous system   autoimmunity   BCMA  

Single-Cell Analysis of Anti-BCMA CAR-T Cell Therapy in Patients with Central Nervous System Autoimmune Diseases Introduction Chimeric Antigen Receptor (CAR) T-cell therapy has shown potential long-term control in treating central nervous system (CNS) autoimmune diseases. This paper investigates the effects of anti-BCMA (B-cell maturation antigen) ...