High Sensitivity of Shotgun Metagenomic Sequencing in Colon Tissue Biopsy by Host DNA Depletion

Medicine, Medical Laboratory Science, Gastroenterology, Life Sciences, Genetics, Microbiology,
host DNA depletion   colon tissue biopsy   shotgun metagenomic sequencing   microbiota   species discovery   disease progression  

High sensitivity of high-throughput metagenomic sequencing in colon tissue biopsies: Eliminating the impact of host DNA Background Evaluating bacterial taxonomic structure through next-generation sequencing without culturing has become a common method for studying the relationship between bacterial imbalance and various diseases. Previous studies h...

Intensity Score of Vessel Wall Contrast Enhancement in MRI Allows Prediction of Disease Progression in Moyamoya Angiopathy

Intensity Score of Vessel Wall Contrast Enhancement in MRI Allows Prediction of Disease Progression in Moyamoya Angiopathy

Medicine, Neurology, Medical Imaging,
vessel wall enhancement   cerebrovascular disease   moyamoya disease   disease progression   stroke risk  

This study explored the value of arterial wall enhancement grading on magnetic resonance imaging in predicting disease progression of moyamoya disease. This was a single-center retrospective cohort study that included 48 patients diagnosed with moyamoya disease who underwent arterial wall imaging and digital subtraction angiography follow-up. The s...

Treatment response as surrogate to predict risk for disease progression in pediatric medulloblastoma with persistent MRI lesions after first-line treatment

Medicine, Pediatrics, Neurosurgery, Medical Imaging, Oncology,
medulloblastoma   persistent lesions   treatment response   disease progression   prognosis prediction  

Response to First-Line Treatment of Persistent MRI Lesions in Pediatric Medulloblastoma as a Surrogate Marker for Predicting Risk of Disease Progression Medulloblastoma is one of the most common malignant central nervous system tumors in children. Although the multimodal treatment concept has significantly improved the prognosis for patients, the o...