International Multicentre Validation of the Left Pancreatectomy Pancreatic Fistula Prediction Models and Development and Validation of the Combined DISPAIR-FRS Prediction Model

Medicine, Hepatobiliary System,
left pancreatectomy   pancreatic fistula   prediction models   multicentre study   DISPAIR-FRS   risk score   postoperative complications  

Academic Background Pancreatectomy is an important treatment for pancreatic diseases, but postoperative pancreatic fistula (POPF) is a common and serious complication, with an incidence rate as high as 20%. POPF not only prolongs hospital stays and increases medical costs but is also closely associated with increased postoperative mortality. Theref...

Preoperative Stereotactic Radiotherapy to Prevent Pancreatic Fistula in High-Risk Patients Undergoing Pancreatoduodenectomy (FIBROPANC): Prospective Multicentre Phase II Single-Arm Trial

Medicine, Hepatobiliary System, Anesthesiology, Gastroenterology, Oncology,
pancreatic fistula   stereotactic radiotherapy   pancreatoduodenectomy   high-risk patients   fibrosis   safety   efficacy  

Pancreaticoduodenectomy is a common surgery for treating tumors of the pancreas and surrounding organs, but postoperative pancreatic fistula (POPF) is one of its major complications, especially in high-risk patients, where the incidence of POPF can be as high as 50%. POPF not only increases hospitalization time and medical costs but can also lead t...