International Multicentre Validation of the Left Pancreatectomy Pancreatic Fistula Prediction Models and Development and Validation of the Combined DISPAIR-FRS Prediction Model

Medicine, Hepatobiliary System,
left pancreatectomy   pancreatic fistula   prediction models   multicentre study   DISPAIR-FRS   risk score   postoperative complications  

Academic Background Pancreatectomy is an important treatment for pancreatic diseases, but postoperative pancreatic fistula (POPF) is a common and serious complication, with an incidence rate as high as 20%. POPF not only prolongs hospital stays and increases medical costs but is also closely associated with increased postoperative mortality. Theref...

Impact of Postoperative Complications on Clinical Outcomes After Gastrectomy for Cancer: Multicentre Study

Medicine, Gastroenterology, Oncology,
gastric cancer   postoperative complications   multicentre study   clinical outcomes   anastomotic leakage   pulmonary complications   30-day mortality  

Gastric cancer is one of the most common malignant tumors worldwide, and surgical resection (gastrectomy) is the primary treatment. Although the application of minimally invasive techniques has reduced surgical trauma, the incidence of postoperative complications after gastrectomy remains high, ranging from 20% to 40%. These complications not only ...

Patient-Reported Outcomes 3 and 18 Months After Mastectomy and Immediate Prepectoral Implant-Based Breast Reconstruction in the UK PRE-BRA Prospective Multicentre Cohort Study

Medicine, Obstetrics and Gynecology, Oncology,
breast reconstruction   patient-reported outcomes   prepectoral implant   multicentre study   mastectomy  

Mastectomy is a common surgical procedure in the treatment of breast cancer, with approximately 55,000 women diagnosed with breast cancer each year in the UK, of whom up to 40% undergo mastectomy. Mastectomy has a profound impact on women’s physical and mental health, and the UK National Institute for Health and Care Excellence (NICE) recommends th...

Clinical and Patient-Reported Outcomes in Women Offered Oncoplastic Breast-Conserving Surgery as an Alternative to Mastectomy: ANTHEM Multicentre Prospective Cohort Study

Medicine, Oncology,
oncoplastic breast-conserving surgery   mastectomy   patient-reported outcomes   multicentre study   breast cancer  

Breast cancer is one of the most common cancers among women worldwide, with over 56,000 women diagnosed annually in the UK. Despite advancements in treatment, approximately 40% of patients still undergo mastectomy. While mastectomy effectively controls cancer, it profoundly impacts patients’ quality of life. Many women describe mastectomy as a “dis...

Multicentre Prospective Study on the Diagnostic and Prognostic Validity of Malnutrition Assessment Tools in Surgery

Medicine, Anesthesiology, Gastroenterology,
malnutrition   surgery   diagnostic tools   prognostic validity   multicentre study   nutritional assessment   postoperative complications  

Academic Background Malnutrition is a significant risk factor for postoperative complications, particularly in patients undergoing major abdominal surgery, where the incidence of malnutrition is high. However, there is currently no widely accepted tool for assessing malnutrition. Existing nutritional screening tools vary greatly in sensitivity and ...

Effect of Perioperative Blood Transfusion on Preoperative Haemoglobin Levels as a Risk Factor for Long-Term Outcomes in Patients Undergoing Major Noncardiac Surgery: A Prospective Multicentre Observational Study

Medicine, Anesthesiology, Cardiovascular System,
perioperative transfusion   preoperative haemoglobin   long-term outcomes   noncardiac surgery   multicentre study   observational study   cardiovascular events  

Academic Background Preoperative anemia and red blood cell (RBC) transfusions are closely associated with poorer surgical outcomes. Although RBC transfusions can increase oxygen delivery, they are also linked to an increased risk of infectious complications, thromboembolic events, pneumonia, sepsis, cardiac events, and mortality. Therefore, when st...