Correlation between PTDP-43 Levels and Cell-Specific Molecular Alterations in the Prefrontal Cortex of C9orf72 ALS/FTD Patients Background Introduction Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two types of progressive neurodegenerative diseases. Their common feature is the loss of specific neuronal populations in th...

Inferring Latent Neural Circuits from Heterogeneous Neural Responses During Cognitive Tasks Academic Background In cognitive tasks, higher cortical areas of the brain (such as the prefrontal cortex, PFC) are responsible for integrating a variety of sensory, cognitive, and motor signals. However, the responses of individual neurons often exhibit com...

Computational Modeling of Prefrontal-Cingulate Coupling: Exploring Its Role in Balancing Emotion and Cognition Academic Background In recent years, emotional processing and cognitive control, which are crucial for maintaining normal social behavior and executive function, have attracted widespread attention. This study explores how the balance betw...