An Organotypic Atlas of Human Vascular Cells

Medicine, Cardiovascular System, Life Sciences, Cell Biology, Immunology,
vascular cells   single-cell transcriptomics   endothelial cells   mural cells   organotypic   molecular signatures   vascular diseases  

Decoding the Human Vascular System: A Comprehensive Multi-organ Single-cell Transcriptomic Study Reveals Vascular Cell Diversity Background Overview The human vascular system is a core component for sustaining life, comprising endothelial cells (ECs) and mural cells that span across all organ systems. Its functions extend beyond merely delivering b...

Analyzing Embryo Dormancy at Single-Cell Resolution Reveals Dynamic Transcriptional Responses and Activation of Integrin-YAP/TAZ Prosurvival Signaling

Life Sciences, Cell Biology, Biochemistry,
embryo dormancy   single-cell transcriptomics   integrin signaling   YAP/TAZ   developmental potential   mouse embryo   transcriptional dynamics  

Dynamic Transcriptional Response and Activation of Integrin-YAP/TAZ Survival Signaling Pathway Revealed by Single-Cell Resolution Analysis of Embryo Dormancy Introduction Embryo dormancy, or diapause, is a unique reproductive adaptation that allows some mammals to pause embryonic development without compromising their developmental potential. Diapa...