The Mevalonate Pathway Contributes to Breast Primary Tumorigenesis and Lung Metastasis

Regulation of the Mevalonate Pathway in Breast Cancer and Its Role in Tumorigenesis and Lung Metastasis Background Introduction Breast cancer is one of the most common cancers among women worldwide, and its occurrence and metastasis mechanisms are complex, involving abnormal regulation of multiple signaling pathways and metabolic processes. In rece...

Fibrotic Response to Anti-CSF-1R Therapy Potentiates Glioblastoma Recurrence

Fibrotic Response to Anti-CSF-1R Therapy Potentiates Glioblastoma Recurrence

Fibrotic Response Induced by Anti-CSF-1R Treatment Promotes Glioblastoma Recurrence Background Introduction Glioblastoma (GBM) is a highly aggressive and malignant primary tumor of the central nervous system. Although current standard treatments include surgical resection, Temozolomide chemotherapy, and fractionated radiotherapy, the median surviva...