Neuronal AMPK Regulates Microglial Lipid Droplet Accumulation in Tauopathy Brain

Accumulation of Lipid Droplets in Microglia is Regulated by Neuronal AMPK Background and Research Question Alzheimer’s Disease (AD) is a common type of dementia characterized by neurofibrillary tangles and β-amyloid plaques. However, beyond these classical pathologies, changes in lipid metabolism are increasingly recognized as closely associated wi...

Doxycycline-loaded calcium phosphate nanoparticles with a pectin coat can ameliorate lipopolysaccharide-induced neuroinflammation via enhancing AMPK

Protective Effect of Doxycycline-Loaded Calcium Phosphate Nanoparticles on LPS-Induced Neuroinflammation in Mice In the field of neuroscience research, neuroinflammation is an important pathological feature of many neurological diseases. Neuroinflammation is a complex response of the central nervous system (CNS) to various damaging triggers (such a...