Intratumoral Antigen Signaling Traps CD8+ T Cells to Confine Exhaustion to the Tumor Site

Intratumoral Antigen Signaling Traps CD8+ T Cells to Confine Exhaustion to the Tumor Site

Research Progress in Cancer Immunology: Tumor-derived Antigen Signals Induce CD8+ T-cell Exhaustion Localized to the Tumor Site Research Background and Purpose In recent years, immunotherapy has shown great potential in cancer treatment. However, tracking the behavior of immune cells after receiving antigen signals remains a challenge. Within tumor...