Site-Specific Genetic and Functional Signatures of Aortic Endothelial Cells at Aneurysm Predilection Sites in Healthy and AngII ApoE−/− Mice Academic Background Aortic aneurysm (AA) is characterized by pathological dilation at specific predilection sites of the vessel, potentially leading to life-threatening vascular rupture. Aortic aneurysms typic...

Multimodal Imaging Study of the Tumor Microenvironment in Colorectal Cancer: Revealing Spatial Heterogeneity Academic Background Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with its complexity and heterogeneity posing significant challenges for treatment and prognosis prediction. The tumor microe...

Cancer Cell International - Review Report Background and Motivation In recent decades, research into cancer evolution has gradually revealed that the evolutionary patterns of cancer cells share many similarities with species evolution. This notion has changed our understanding of tumor evolution and heterogeneity. Cancer is initiated by the mutatio...