Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy

Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy

This study utilized a machine learning framework to explore the underlying cell states and cellular ecosystems constituting soft tissue sarcomas, and associated them with patient prognosis and response to immunotherapy. Research Background: Soft tissue sarcomas are rare and highly heterogeneous malignancies of connective tissues, with limited syste...