Tumor Architecture and Microenvironment Features in Brain Metastasis of Breast Cancer

Tumor Architecture and Microenvironment Features in Brain Metastasis of Breast Cancer

Specific Tumor Structures and Microenvironment of Breast Cancer Metastasis to the Brain: A Research Review Research Background Brain metastasis is one of the severe complications faced by breast cancer patients, leading to complex neurological complications and low survival rates, with very limited treatment options. Among the various subtypes of b...

Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy

Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy

This study utilized a machine learning framework to explore the underlying cell states and cellular ecosystems constituting soft tissue sarcomas, and associated them with patient prognosis and response to immunotherapy. Research Background: Soft tissue sarcomas are rare and highly heterogeneous malignancies of connective tissues, with limited syste...