Context-Dependent Roles of Mitochondrial LonP1 in Orchestrating the Balance Between Airway Progenitor Versus Progeny Cells

Medicine, Respiratory System, Life Sciences, Cell Biology, Biochemistry, Immunology,
mitochondrial deficiency   airway progenitor cells   Bok expression   COPD   LonP1   stress response   cell imbalance  

Background and Problem In recent years, there has been significant progress in research on the multifaceted roles of mitochondria within cells. Aside from being the energy source of the cell, mitochondria also play crucial regulatory roles in processes such as cell proliferation, differentiation, and self-renewal, attracting widespread attention in...

Association of EIF2AK3 Variants with Neurocognitive Impairment in People Living with HIV

Medicine, Infectious Diseases, Neurology, Life Sciences, Cell Biology, Biochemistry, Immunology,
EIF2AK3   single nucleotide variants   HIV   neurocognitive impairment   stress response   genetic variation  

Research Report on the Association between Gene Variants and Neurocognitive Impairment in HIV Patients Over the past few decades, antiretroviral therapy (ART) has greatly improved the health of people infected with human immunodeficiency virus (HIV). However, even with effective viral suppression and partial immune system recovery, up to 50% of Peo...

YEATS2 Knockdown Impairs Dopaminergic Synaptic Integrity and Leads to Seizure-like Behaviors in Drosophila Melanogaster

Medicine, Basic Medical Sciences, Neurology, Life Sciences, Biochemistry, Genetics,
YEATS2 gene   dopamine   Drosophila   synaptic integrity   epilepsy   stress response  

A Study on the Effect of YEATS2 Gene Knockdown on Dopaminergic Synaptic Integrity and Epileptic-like Behavior in Drosophila Background Introduction Epilepsy is a common neurological disorder characterized by abnormal electrical activities in the brain. These abnormal activities can lead to seizures and other neurological symptoms. Familial adult my...