Sex Differences in the Risk of Stroke Associated with Traditional and Non-Traditional Factors in a US Cohort of People with HIV Infection

Medicine, Infectious Diseases, Neurology, Cardiovascular System,
HIV   stroke   sex differences   cardiovascular risk   lifestyle factors   HIV viremia  

Study on Gender Differences and Stroke Risk Among HIV-Infected Individuals Background Individuals with HIV infection may face a higher risk of stroke, particularly women. However, understanding of whether the influence of various factors on cerebrovascular risk in this population differs by gender and whether these differences contribute to variati...

Gene Expression Alterations in the Spinal Cord of SIV-Infected Macaques on Antiretroviral Therapy

Medicine, Infectious Diseases, Neurology, Life Sciences, Cell Biology, Immunology,
SIV   HIV   spinal cord   antiretroviral therapy   gene expression   neuropathy  

NARP Laboratory Research Reveals the Impact of SIV Infection on Spinal Cord Gene Expression Background Despite the implementation of antiretroviral therapy (ART), HIV-associated peripheral neuropathy (HIV-DSP) remains one of the most common neurological manifestations of HIV infection. Clinical symptoms of HIV-DSP include weakness, numbness, burnin...

Association of EIF2AK3 Variants with Neurocognitive Impairment in People Living with HIV

Medicine, Infectious Diseases, Neurology, Life Sciences, Cell Biology, Biochemistry, Immunology,
EIF2AK3   single nucleotide variants   HIV   neurocognitive impairment   stress response   genetic variation  

Research Report on the Association between Gene Variants and Neurocognitive Impairment in HIV Patients Over the past few decades, antiretroviral therapy (ART) has greatly improved the health of people infected with human immunodeficiency virus (HIV). However, even with effective viral suppression and partial immune system recovery, up to 50% of Peo...

mRNA-LNP Prime Boost Evolves Precursors Toward VRC01-Like Broadly Neutralizing Antibodies in Preclinical Humanized Mouse Models

Medicine, Infectious Diseases, Rheumatology and Immunology, Life Sciences, Immunology, Microbiology,
mRNA vaccines   broadly neutralizing antibodies   preclinical humanized mouse models   HIV   immunology   lipid nanoparticles  

Inducing and Optimizing VRC01-like Broadly Neutralizing Antibodies in Mouse Models with mRNA-LNP Background Introduction In recent years, the importance of acquiring broadly neutralizing antibodies (bnAbs) has been increasingly recognized in vaccine development, particularly in the field of HIV (Human Immunodeficiency Virus) vaccine research. The H...