Dual Ferroptosis Induction in N2-TANs and TNBC Cells via FTH1 Targeting: A Therapeutic Strategy for Triple-Negative Breast Cancer

Chemistry, Medicinal Chemistry, Medicine, Pharmacy, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
ferroptosis   triple-negative breast cancer   N2-TANs   FTH1   immune microenvironment   ferritinophagy   novel cancer therapy  

Dual Ferroptosis Induction via FTH1 Targeting: A New Therapeutic Strategy for Triple-Negative Breast Cancer (TNBC) Background: Why Conduct This Study? Breast cancer is one of the most common cancer types worldwide, accounting for 11.7% of all new cancer cases globally. Among its several subtypes, triple-negative breast cancer (TNBC) stands out for ...

Targeting SNRNP200-Induced Splicing Dysregulation as an Immunotherapy Opportunity for Glycolytic Triple-Negative Breast Cancer

Medicine, Infectious Diseases, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics,
triple-negative breast cancer   SNRNP200   glycolysis   metabolic dysregulation   immunotherapy  

Targeting SNRNP200-Induced Splicing Dysregulation: A New Strategy for Immunotherapy in Glycolytic Triple-Negative Breast Cancer Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, characterized by extremely high recurrence and mortality rates. Despite significant recent advances in research on TNBC subty...