Single-Cell RNA Sequencing and Machine Learning Reveal Relationship Between CD8+ T Cells and Uveal Melanoma Metastasis

Medicine, Oncology,
single-cell RNA sequencing   uveal melanoma   metastasis risk   immune microenvironment   CD8+ T cells   machine learning   tumor microenvironment  

Academic Report on “Machine Learning and Single-cell RNA Sequencing Reveal Relationship Between Intratumor CD8+ T Cells and Uveal Melanoma Metastasis” published in Cancer Cell International in 2024 Research Background and Purpose Uveal melanoma (UM) is the most common intraocular malignant tumor in adults. After receiving radiation or surgical trea...

Depleting Profibrotic Macrophages Using Bioactivated In Vivo Assembly Peptides Ameliorates Kidney Fibrosis

Medicine, Rheumatology and Immunology, Basic Medical Sciences, Nephrology, Life Sciences, Cell Biology, Biochemistry, Immunology,
renal fibrosis   immune microenvironment   profibrotic macrophage   bioactivated in vivo assembly   cell death  

Preface Chronic Kidney Disease (CKD) is a condition characterized by long-term damage to kidney structure, leading to gradual loss of kidney function. Currently, about 10% of adults worldwide are affected by CKD, causing approximately 1.2 million deaths annually. Renal fibrosis is one of the pathological manifestations of CKD, characterized by the ...