Raman-Based Machine Learning Platform Reveals Unique Metabolic Differences Between IDHmut and IDHwt Glioma

Study on Metabolic Differences between IDH Mutant and Wild-type Glioma Cells Using Raman Spectroscopy and Machine Learning Platform Background Introduction In the diagnosis and treatment of gliomas, formalin-fixed, paraffin-embedded (FFPE) tissue sections are commonly used. However, due to background noise interference from the embedding medium, th...

Diffusion-based Deep Learning Method for Augmenting Ultrastructural Imaging and Volume Electron Microscopy

Diffusion-based Deep Learning Method for Augmenting Ultrastructural Imaging and Volume Electron Microscopy

Enhancing Super-Resolution Imaging and Volume Electron Microscopy with Deep Learning Algorithms Based on Diffusion Models Background Introduction Electron Microscopy (EM) as a high-resolution imaging tool has made significant breakthroughs in cell biology. Traditional EM techniques are primarily used for two-dimensional imaging, and although they h...

A Novel CNN-Based Image Segmentation Pipeline for Individualized Feline Spinal Cord Stimulation Modeling

Automated Spinal Cord Segmentation Pipeline Based on Convolutional Neural Network (CNN) for Individualized Cat Spinal Cord Stimulation Modeling Background and Research Motivation Spinal cord stimulation (SCS) is a widely used treatment method for chronic pain management. In recent years, it has also been used to modulate neural activity, aiming to ...

Attention-Guided Graph Structure Learning Network for EEG-enabled Auditory Attention Detection

Attention-Guided Graph Structure Learning Network for EEG-enabled Auditory Attention Detection

Application of Attention-guided Graph Structure Learning Network for EEG-enabled Auditory Attention Detection Academic Background The “cocktail party effect” describes the human brain’s ability to selectively concentrate attention on one speaker while ignoring others in a multi-talker environment. However, for individuals with hearing impairments, ...

A Systematic Evaluation of Euclidean Alignment with Deep Learning for EEG Decoding

Systematic Evaluation of Euclidean Alignment with Deep Learning for EEG Decoding Background Introduction Electroencephalogram (EEG) signals are widely used in brain-computer interface (BCI) tasks due to their non-invasive nature, portability, and low acquisition cost. However, EEG signals suffer from low signal-to-noise ratio, sensitivity to electr...

Changes in Brain Functional Networks Induced by Visuomotor Integration Task

Frequency-Specific Reorganization of Brain Networks during Visuomotor Tasks Research Background Executing movements is a complex cognitive function that relies on the coordinated activation of spatially proximal and distal brain regions. Visuomotor integration tasks require processing and interpreting visual inputs to plan motor execution and adjus...

Bayesian Estimation of Group Event-Related Potential Components: Testing a Model for Synthetic and Real Datasets

Background Introduction The study of Event-Related Potentials (ERPs) provides important information about brain mechanisms, particularly in elucidating various psychological processes. In these studies, multi-channel electroencephalograms (EEGs) are typically recorded while subjects perform specific tasks, and the trials are categorized based on st...

Neuronal Functional Connectivity is Impaired in a Layer-dependent Manner Near Chronically Implanted Intracortical Microelectrodes in C57BL/6 Wildtype Mice

Layer-Dependent Effects of Chronic Neural Electrode Implants on Neural Functional Connectivity in Mice Introduction This study explores the long-term effects of chronically implanted microelectrodes on neural functional connectivity within the brains of C57BL6 wild-type mice. Implanted intracerebral electrodes enable the recording and electrical st...

GCTNet: A Graph Convolutional Transformer Network for Major Depressive Disorder Detection Based on EEG Signals

GCTNet: Graph Convolution Transformer Network for Detecting Major Depressive Disorder Based on EEG Signals Research Background Major Depressive Disorder (MDD) is a prevalent mental illness characterized by significant and persistent low mood, affecting over 350 million people worldwide. MDD is one of the leading causes of suicide, resulting in appr...

Topology of Surface Electromyogram Signals: Hand Gesture Decoding on Riemannian Manifolds

Topology of Surface Electromyography Signals: Decoding Hand Gestures Using Riemannian Manifolds This paper is authored by Harshavardhana T. Gowda (Department of Electrical and Computer Engineering, University of California, Davis) and Lee M. Miller (Center for Mind and Brain Sciences, Department of Neurophysiology and Behavior, Department of Otolar...