Retrospective Study of Claudin 18 Isoform 2 Prevalence and Prognostic Association in Gastric and Gastroesophageal Junction Adenocarcinoma

Medicine, Oncology, Life Sciences, Biochemistry, Immunology,
gastric cancer   gastroesophageal junction adenocarcinoma   claudin 18   biomarkers   prognosis   immunohistochemistry   therapeutic target  

Research Report on Claudin 18.2 in Gastric Cancer and Gastroesophageal Junction Adenocarcinoma Background Introduction Gastric cancer and gastroesophageal junction (G/GEJ) adenocarcinoma are major global health burdens. It is estimated that in 2020 alone, there were approximately 1.7 million new cases of gastric and esophageal cancers worldwide, wi...

Decreased Microvascular Claudin-5 Levels in Cerebral Amyloid Angiopathy Associated with Intracerebral Haemorrhage

Medicine, Neurology, Neurosurgery, Life Sciences, Biochemistry,
blood–brain barrier   cerebral amyloid angiopathy   claudin-5   immunohistochemistry   intracerebral haemorrhage  

Study on Cerebral Amyloid Angiopathy (CAA) and the Level of Tight Junction Protein Claudin-5 in Microvessels Background Cerebral Amyloid Angiopathy (CAA) is a disease caused by the deposition of Amyloid-β (Aβ) in the cerebral blood vessels. Research indicates that approximately 23% of individuals over the age of 55 have moderate to severe CAA. CAA ...