Radiation-Induced Cellular Plasticity Primes Glioblastoma for Forskolin-Mediated Differentiation Academic Background Glioblastoma (GBM) is one of the deadliest brain cancers in adults, with a median survival period of only 15 to 18 months for patients. Although surgery combined with chemoradiotherapy can delay disease progression, these treatments ...

High Cellular Plasticity State of Pediatric Medulloblastoma: A Comprehensive Analysis of Local Recurrence and Distant Dissemination Research Background Medulloblastoma (MB) is a highly heterogeneous pediatric intracranial malignancy. While current treatments (surgery, radiotherapy, and chemotherapy) improve survival rates after initial treatment, r...

Research Report: The Regulatory Role of ROR2 in Pancreatic Cancer Cell Plasticity Background Introduction Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with most patients lacking the possibility of a cure. This is partly due to the difficulty in early detection. One of the characteristics of PDAC is its extensive tumor cell heterogene...