The Role of Diabetes and Age in Early Coronary Revascularization Among 'Stable' Patients with Non-ST-Segment Elevation Acute Coronary Syndromes

Academic Background Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a common cardiovascular disease, particularly among diabetic patients, whose incidence and mortality rates are significantly higher than those of non-diabetic patients. Although current clinical guidelines recommend early (within 24 hours) coronary revascularization ...

Cycling Alpha Cells in Regenerative Drug-Treated Human Pancreatic Islets May Serve as Key Beta Cell Progenitors

Academic Background Diabetes is a global health issue affecting over 500 million people. Both type 1 diabetes (T1D) and type 2 diabetes (T2D) share the common feature of a significant reduction in the number of functional insulin-secreting beta cells. Therefore, restoring or increasing beta cell mass is considered a key strategy in diabetes treatme...

Aging Promotes Metabolic Dysfunction-Associated Steatotic Liver Disease by Inducing Ferroptotic Stress

Aging Promotes Metabolic Dysfunction-Associated Steatotic Liver Disease by Inducing Ferroptotic Stress

Research Review on Aging-Exacerbated Metabolic Dysfunction-Related Lipid Liver Diseases Academic Background As the aging population increases, metabolic diseases induced by aging are becoming a severe public health challenge. The liver, being the primary metabolic organ, requires special attention to its functional disorders during aging. Studies h...