The Lifetime Risk of Surgery in England: A Nationwide Observational Cohort Study

Lifetime Risk of Surgery in England: A Nationwide Observational Cohort Study Academic Background Surgery represents a significant portion of the UK National Health Service (NHS) activity, with approximately 4.4 million people undergoing surgical procedures in England each year. Although an increasing number of surgeries are performed as day-case pr...

Perioperative levels of IL8 and IL18, but not IL6, are associated with nucleus basalis magnocellularis atrophy three months after surgery

Association Study of Perioperative IL8 and IL18 Levels with Brain Basal Ganglia Atrophy Three Months After Surgery Background In recent years, an increasing number of studies have shown that surgical procedures may accelerate brain atrophy. Meanwhile, the relationship between systemic inflammation and neurodegenerative diseases has also received co...

Connectome Reorganization Associated with Temporal Lobe Pathology and Its Surgical Resection

Connectome Reorganization Associated with Temporal Lobe Pathology and Its Surgical Resection

Connectomics Reconstruction Associated with Temporal Lobe Lesions and Their Surgical Resection Academic Background The human brain’s structural organization is increasingly conceptualized and analyzed from a network perspective, greatly enhancing understanding of health and disease. In recent years, thanks to advances in neuroimaging technology and...

Mapping Interictal Discharges Using Intracranial EEG-fMRI to Predict Postsurgical Outcomes

Mapping Interictal Discharges Using Intracranial EEG-fMRI to Predict Postsurgical Outcomes

Using Intracranial EEG-fMRI Mapping of Intermittent Discharges to Predict Epilepsy Surgery Outcomes Background and Objective Epilepsy is a common neurological disorder, and many patients are unresponsive to pharmacological treatments, making surgery one of the primary therapeutic options. However, accurately localizing the seizure onset zone (SOZ) ...