Study on the Propagation of Neuronal Micronuclei Regulating Microglial Characteristics Academic Background Microglia, the resident immune cells in the central nervous system (CNS), play a crucial role in maintaining brain homeostasis, regulating neuronal development, synaptic pruning, and responding to pathological states. However, despite extensiv...
A Cross-Tissue Transcriptome-Wide Association Study Identifies New Susceptibility Genes for Insomnia Background Insomnia is the second most prevalent psychiatric disorder, affecting nearly one-third of the global population. It not only diminishes quality of life but also increases the risk of cardiovascular diseases, metabolic disorders, mood diso...
The Application of Proton Magnetic Resonance Spectroscopy in Fetal and Neonatal Brain Research Background Introduction The brain undergoes rapid biochemical and structural changes during fetal and neonatal development. These changes are crucial for understanding normal development and the mechanisms underlying neurological disorders. However, tradi...
The Role of the Neonatal Gut Microbiota in the Encephalopathy of Prematurity: A Comprehensive Study Academic Background Premature birth (defined as birth before 37 weeks of gestation) is a common issue globally, affecting approximately 10% of pregnancies. Preterm infants are at risk of abnormal brain development, known as Encephalopathy of Prematur...
Research Background Neural oscillations are fundamental components of brain function, coordinating electrophysiological activities within and between neural assemblies, which is crucial for cognitive and behavioral processes. During children’s growth, the development of these neural processes is not only an important neuroscience issue but also can...
Linking Healthy Neurodevelopment with Imaging, Transcriptomic, and Genetic Associations in Autism Spectrum Disorder and Schizophrenia: A Study of Cortical Gene Expression Patterns Background: How does the complex anatomy and functional organization of the human brain develop from the expression of more than 20,000 genes? And how does this process g...