Inflammatory Mechanisms in Traumatic Brain Injury and Post-Traumatic Epilepsy: A Study

Medicine, Rheumatology and Immunology, Neurology, Neurosurgery, Life Sciences, Biochemistry, Immunology,
Traumatic Brain Injury   Post-Traumatic Epilepsy   Inflammasome Signaling   Microglia   NLRP3  

Neuroinflammation and Epilepsy: The Role of Inflammasomes in Traumatic Brain Injury Background and Purpose Traumatic Brain Injury (TBI) refers to changes in brain function and pathology resulting from physical trauma to the head or neck. Apart from common behavioral and psychological disorders, post-traumatic epilepsy (PTE) is one of the most sever...

Early Depletion of Gut Microbiota Shapes Oligodendrocyte Response After Traumatic Brain Injury

Medicine, Rheumatology and Immunology, Neurology, Neurosurgery, Life Sciences, Cell Biology, Immunology, Microbiology,
Traumatic Brain Injury   White Matter Injury   Gut Microbiota   T Cells   Oligodendrocytes   Neuroinflammation   Remyelination  

Study on the Role of Gut Microbiota in White Matter Repair after Traumatic Brain Injury - Analysis of “Journal of Neuroinflammation” Introduction Every year, around 1.7 million people in the United States experience traumatic brain injury (TBI), with over 5 million facing disability issues related to TBI. These non-fatal TBIs are estimated to incur...

Systemic Administration of Soluble Glycoprotein 130 in Traumatic Brain Injury: Effects on Cognitive Performance and Chemokine Levels

Medicine, Rheumatology and Immunology, Medical Laboratory Science, Neurology, Neurosurgery, Life Sciences, Immunology,
Traumatic Brain Injury   Soluble Glycoprotein 130   Cognitive Performance   Chemokine Levels   Neuroinflammation  

Research Review: Treating Traumatic Brain Injury through Selective Inhibition of IL-6 Pathway Background Traumatic brain injury (TBI) is one of the leading causes of long-term neurological damage and death globally, with no effective disease-modifying treatments currently available. TBI patients often suffer from cognitive, behavioral, and sensory ...

Prevotella copri Transplantation Promotes Neurorehabilitation in a Mouse Model of Traumatic Brain Injury

Medicine, Basic Medical Sciences, Neurology, Life Sciences,
Prevotella copri   Traumatic Brain Injury   Gut Microbiota   Neurorehabilitation   Antioxidant   PI3K/AKT Pathway  

Journal of Neuroinflammation Research Report: Neuroprotective Effects of Prevotella copri Transplantation in a Traumatic Brain Injury Mouse Model Background Traumatic brain injury (TBI) affects over 50 million people globally each year and is considered a significant public health challenge. Secondary injuries associated with TBI are largely relate...

Study on the Effects of Traumatic Brain Injury on Chronic Meningeal CLIP+ B Cells, Neuropathology, and Neurobehavioral Impairment in 5xFAD Mice

Medicine, Rheumatology and Immunology, Neurology, Medical Imaging, Life Sciences, Biochemistry, Immunology,
Traumatic Brain Injury   Alzheimer's Disease   B Cells   Neuropathology   Neurobehavioral Impairment   Immune Response   5xFAD Mice  

Research Report: Long-Term Effects of Class II Invariant Peptide (CLIP) Antagonism on CLIP+ B Cells in the Meninges, Neuropathology, and Neurobehavioral Deficits in 5xFAD Mice Research Background Traumatic brain injury (TBI) is a significant public health problem affecting millions of individuals worldwide each year. More importantly, TBI is a sign...

Inhibition of Mannan-Binding Lectin Associated Serine Protease-2 Reduces Cognitive Deficits in a Mouse Model of Severe Traumatic Brain Injury

Medicine, Neurology, Neurosurgery, Life Sciences, Immunology,
Traumatic Brain Injury   Lectin Pathway   MASP-2   Cognitive Deficits   Antibody Therapy   Mouse Model  

Review of Research on the Treatment Potential for Cognitive Deficits in Traumatic Brain Injury Research Background Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. In Europe, the annual incidence of TBI is at least 4 million cases, imposing a heavy burden on patients, society, and health systems, yet the available ...

AI-based Denoising of Head Impact Kinematics Measurements with Convolutional Neural Network for Traumatic Brain Injury Prediction

Information Science, Artificial Intelligence, Medicine, Neurosurgery, Life Sciences, Bioengineering,
AI   Convolutional Neural Network   Head Impact   Traumatic Brain Injury   Denoising   Kinematics Measurements  

Research and Application of Denoising Head Impact Kinematics Measurement Based on Convolutional Neural Networks Research Background Mild Traumatic Brain Injury (MTBI) is a global health threat. Humans often face the risk of MTBI in situations such as falls, traffic accidents, and sports. According to statistics, there were over 27 million brain inj...