Phase Ib Trial of Neoadjuvant Oncolytic Virus OrienX010 and Toripalimab in Resectable Acral Melanoma

Neoadjuvant Oncolytic Virus OrienX010 Combined with PD-1 Inhibitor Toripalimab for Resectable Acral Melanoma: Phase Ib Clinical Trial Background Acral melanoma (AM) is a highly aggressive subtype of melanoma with a high incidence in the Chinese population, accounting for approximately 40% of melanoma cases. Despite advances in melanoma treatment, c...

Integrative Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interplay of In Situ and Invasive Acral Melanoma

Integrative Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interplay of In Situ and Invasive Acral Melanoma

Integrated Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interactions in In Situ and Invasive Acral Melanoma Academic Background of the Paper Melanoma is a type of skin cancer, and acral melanoma (AM) is a kind that occurs on non-exposed areas such as the palms, soles, and under the nails and is particularly common a...