Comparison of Long-Term Survival of Neoadjuvant Therapy Plus Surgery Versus Upfront Surgery and the Role of Adjuvant Therapy for T1b-2N0-1 Esophageal Cancer: A Population Study of the SEER Database and Chinese Cohort

Medicine, Gastroenterology, Oncology,
esophageal cancer   neoadjuvant therapy   surgery   survival rate   prognosis   SEER database   Chinese cohort  

Comparative Study on Treatment Strategies for Esophageal Cancer Academic Background Esophageal cancer is one of the digestive system tumors with high incidence and mortality rates worldwide, particularly in Asia, where the incidence of esophageal squamous cell carcinoma (SCC) is notably prominent. Although significant progress has been made in the ...

Phase Ib Trial of Neoadjuvant Oncolytic Virus OrienX010 and Toripalimab in Resectable Acral Melanoma

Medicine, Rheumatology and Immunology, Basic Medical Sciences, Oncology, Life Sciences, Bioengineering, Immunology, Microbiology,
acral melanoma   neoadjuvant therapy   oncolytic virus   PD-1 inhibitors   tumor microenvironment   recurrence-free survival   safety  

Neoadjuvant Oncolytic Virus OrienX010 Combined with PD-1 Inhibitor Toripalimab for Resectable Acral Melanoma: Phase Ib Clinical Trial Background Acral melanoma (AM) is a highly aggressive subtype of melanoma with a high incidence in the Chinese population, accounting for approximately 40% of melanoma cases. Despite advances in melanoma treatment, c...