CD137L Inhibition Ameliorates Hippocampal Neuroinflammation and Behavioral Deficits in a Mouse Model of Sepsis-Associated Encephalopathy

Medicine, Infectious Diseases, Neurology, Life Sciences, Cell Biology, Immunology,
CD137L   microglia   inflammation   anxiety   cognition   TKS-1  

Background Introduction Sepsis is a life-threatening multiple organ dysfunction syndrome caused by uncontrolled infection in the host, and is one of the leading causes of death in intensive care units. It is reported that there are approximately 189 adult sepsis hospitalization cases per 100,000 person-years, with a mortality rate of 26.7%. Sepsis-...

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization

Medicine, Environmental and Public Health, Psychiatry, Clinical Psychology,
poverty   mental illness   Mendelian randomization   UK Biobank   anxiety   schizophrenia   socio-economic status  

Study on the Impact of Poverty on Mental Illness: A Mendelian Randomization Analysis Based on the UK Biobank This article aims to explore the causal relationship between poverty and mental illness. Although many studies have shown an association between low socioeconomic status and mental illnesses, most studies have failed to determine whether pov...

Spatiotemporal Responses to Emotional Conflict and Its Psychiatric Correlates in Adolescents with Epilepsy Using Magnetoencephalography

Spatiotemporal Responses to Emotional Conflict and Its Psychiatric Correlates in Adolescents with Epilepsy Using Magnetoencephalography

Medicine, Psychiatry, Neurology, Clinical Psychology, Medical Imaging,
epilepsy   adolescence   emotional conflict regulation   magnetoencephalography   depression   anxiety   cluster-based permutation tests  

Spatio-Temporal Responses of Emotional Conflict and Psychiatric Correlation in Adolescent Epilepsy Patients Research Background Epilepsy patients often experience comorbid mental disorders such as depression and anxiety, which negatively impact their quality of life. Emotional regulation is a critical cognitive process that is frequently impaired i...