GCN2-SLC7A11 Axis Coordinates Autophagy, Cell Cycle, and Apoptosis and Regulates Cell Growth in Retinoblastoma upon Arginine Deprivation

Medicine, Ophthalmology, Oncology, Life Sciences, Cell Biology, Biochemistry,
GCN2   SLC7A11   retinoblastoma   arginine deprivation   autophagy   cell cycle   apoptosis  

GCN2-SLC7A11 Axis Regulates Cell Growth and Survival in Retinoblastoma Under Arginine Deprivation Background Retinoblastoma (RB) is a common intraocular malignant tumor in children, accounting for 4% of all childhood cancers. Although current treatments such as chemotherapy are effective in some patients, they have drawbacks such as multidrug resis...