Multimodal Disentangled Variational Autoencoder with Game Theoretic Interpretability for Glioma Grading

Application of Multi-modal Disentangled Variational Autoencoder and Game Theory Interpretability in Glioma Grading Background Gliomas are the most common primary brain tumors in the central nervous system. According to cellular activity and invasiveness, the World Health Organization (WHO) classifies them into grades I to IV, with grades I and II r...

A Fully Automated Multimodal MRI-Based Multi-task Learning for Glioma Segmentation and IDH Genotyping

A Fully Automated Multimodal MRI-Based Multi-task Learning for Glioma Segmentation and IDH Genotyping

Research Report on Fully Automated Multimodal MRI Multi-task Learning for Glioma Segmentation and IDH Gene Typing Background of the Study Glioma is the most common primary brain tumor in the central nervous system. According to the World Health Organization (WHO) 2016 classification, gliomas are divided into low-grade gliomas (LGG, grades II and II...

An Attention-Guided CNN Framework for Segmentation and Grading of Glioma Using 3D MRI Scans

Study of Attention-Guided CNN Framework for 3D MRI Glioma Segmentation and Grading Gliomas are the most deadly form of brain tumors in humans. Timely diagnosis of these tumors is a crucial step for effective tumor treatment. Magnetic Resonance Imaging (MRI) typically provides a non-invasive examination of brain lesions. However, manual inspection o...

CaNet: Context Aware Network for Brain Glioma Segmentation

CaNet: Context Aware Network for Brain Glioma Segmentation

Context-Aware Network Study Report for Glioma Segmentation Glioma is a common type of adult brain tumor that severely harms health and has a high mortality rate. To provide sufficient evidence for early diagnosis, surgical planning, and postoperative observation, multimodal Magnetic Resonance Imaging (MRI) has been widely applied in this field. The...

Empowering Glioma Prognosis with Transparent Machine Learning and Interpretative Insights Using Explainable AI

Enabling Explainable Artificial Intelligence for Glioma Prognosis: Translational Insights from Transparent Machine Learning Academic Background This study is dedicated to developing a reliable technique to detect whether patients have a specific type of brain tumor—glioma—using various machine learning methods and deep learning methods, combined wi...

Fluorescence Molecular Tomography Based on Group Sparsity Priori for Morphological Reconstruction of Glioma

Report on the Study of Fluorescence Molecular Tomography for Morphological Reconstruction of Glioma Based on Group Sparsity Priors 1. Academic Background and Research Motivation Fluorescence Molecular Tomography (FMT) is an important tool in life sciences that allows non-invasive real-time three-dimensional (3D) visualization of fluorescence source...

Glioma Survival Analysis Empowered with Data Engineering—A Survey

Survival Analysis of Glioblastoma Patients: An Overview Empowered by Data Engineering Introduction Glioblastoma is a type of tumor that occurs in glial cells and accounts for 26.7% of all primary brain and central nervous system tumors. Survival analysis of glioblastoma patients is a key task in clinical management due to the heterogeneity of the t...

Deep Learning of Imaging Phenotype and Genotype for Predicting Overall Survival Time of Glioblastoma Patients

Deep Learning of Imaging Phenotype and Genotype for Predicting Overall Survival Time of Glioblastoma Patients

Globally, the most common and deadly malignant brain tumor is glioblastoma (Glioblastoma, GBM). In recent years, research has continuously attempted to predict the overall survival time (OS) of GBM patients using machine learning techniques based on preoperative single-modality or multi-modality imaging phenotypes. Although these machine learning m...

St. Jude Survivorship Portal: Sharing and Analyzing Large Clinical and Genomic Datasets from Pediatric Cancer Survivors

St. Jude Survivorship Portal: Sharing and Analyzing Large Clinical and Genomic Datasets from Pediatric Cancer Survivors

St. Jude Survivorship Portal: Analysis and Sharing of Large-Scale Clinical and Genomic Data of Pediatric Cancer Survivors Research Background In the United States, the five-year survival rate for childhood cancer has increased from about 60% in the 1970s to over 85% today. Despite the significant improvement in survival rates, these childhood cance...

Identification of Clonal Hematopoiesis Driver Mutations Through In Silico Saturation Mutagenesis

Introduction In the process of healthy hematopoiesis, a group of hematopoietic stem cells (HSC) contribute to all blood-related lineages. However, as we age, this process often leads to clonal hematopoiesis (CH), meaning the expansion of clones originating from a particular HSC, which then occupies a significant portion of blood cells and platelets...