Circulating Extracellular Vesicles as Promising Biomarkers for Precision Diagnostics: A Perspective on Lung Cancer

Medicine, Respiratory System, Oncology, Life Sciences, Biochemistry, Bioengineering, Immunology, Genetics, Biophysics,
extracellular vesicles   lung cancer   liquid biopsy   biosensors   early detection   precision medicine   nanotechnology  

Exosomes as Biomarkers for Precision Diagnosis of Lung Cancer Academic Background Lung cancer is one of the leading causes of cancer-related deaths worldwide, with early diagnosis and precision treatment of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) remaining significant challenges. Although traditional tissue biopsy is co...

Liquid Biopsy versus CT: Comparison of Tumor Burden Quantification in 1065 Patients with Metastases

Medicine, Medical Imaging, Oncology,
liquid biopsy   tumor burden   CT scan   metastatic cancer   quantification  

Comparison of Tumor Burden Quantification between Liquid Biopsy and CT Academic Background In the era of precision medicine, the validation of non-invasive biomarkers faces numerous challenges. Tumor burden, as a potential prognostic marker, has been demonstrated to hold significant value in various studies. Tumor burden refers to the total amount ...

Genome-Wide Repeat Landscapes in Cancer and Cell-Free DNA

Genome-Wide Repeat Landscapes in Cancer and Cell-Free DNA

Medicine, Basic Medical Sciences, Oncology, Life Sciences, Genetics,
cancer   genome-wide repeats   cell-free DNA   liquid biopsy   early detection   structural variant   epigenetics  

A Panoramic View of Whole Genome Repetitive Sequences in Cancer and Circulating Free DNA Research Background and Significance Throughout the development of cancer and other diseases, genetic changes in repetitive sequences within the genome are a significant characteristic. However, standard sequencing methods struggle to effectively characterize t...