Real-Time Detection of Trace Analytes Using Molecular-Antenna-Enhanced Photothermal Spectroscopy

Real-Time Detection of Trace Analytes Using Molecular-Antenna-Enhanced Photothermal Spectroscopy

Real-Time Detection of Trace Analytes Using Molecular-Antenna-Enhanced Photothermal Spectroscopy Academic Background In environmental and safety monitoring, real-time, highly selective, and highly sensitive detection of trace gaseous compounds is a significant challenge. Particularly for emerging environmental pollutants such as per- and polyfluoro...

A Proof-of-Concept Study for Precise Mapping of Pigmented Basal Cell Carcinoma in Asian Skin Using Multispectral Optoacoustic Tomography Imaging with Level Set Segmentation

A Proof-of-Concept Study for Precise Mapping of Pigmented Basal Cell Carcinoma in Asian Skin Using Multispectral Optoacoustic Tomography Imaging with Level Set Segmentation

A New Approach to Skin Cancer Diagnosis: Research on Photoacoustic Imaging with Level Set Segmentation Algorithm In recent years, with global population aging and environmental changes, the incidence rate of skin cancer has been climbing annually. As a significant public health issue, skin cancer primarily manifests in non-melanoma types like squam...

Prediction of Monocular Defocus Curves in Pseudophakia with Different Pupil Sizes

Background With the widespread adoption of cataract surgery and lens replacement surgery, the optical performance of intraocular lenses (IOLs) has become increasingly critical in determining patients’ postoperative visual quality. Predicting clinical visual performance (such as visual acuity and defocus range) is an emerging area of interest in oph...

Compact and Aberration Effects-Shielded Objective Intraocular Scatter Measurement System

Research Advances on a Novel Compact Double-Pass Intraocular Scatter Measurement System Academic Background According to the World Health Organization (WHO), cataracts are the leading cause of blindness globally, accounting for approximately 50% of all blindness cases. More than 20 million people worldwide suffer from vision loss or severe impairme...

Challenging the Skin Pigmentation Bias in Tissue Oximetry via Time-Domain Near-Infrared Spectroscopy

Challenging Skin Pigmentation Bias: Application of Time-Domain Near-Infrared Spectroscopy in Tissue Oximetry Background and Motivation In recent years, optical technologies have been increasingly utilized in medical diagnostics and therapies. However, varying levels of skin pigmentation (which depend on melanin concentration in the skin) can signif...

Demonstration of Femtosecond Laser Induced Refractive Index Change in Silk-Fibroin Hydrogels

Demonstration of Femtosecond Laser Induced Refractive Index Change in Silk-Fibroin Hydrogels: A New Hope for Future Ophthalmic Biocompatible Implants In today’s era of advanced biotechnology and rapid developments in the biomedical field, refractive correction techniques have become a global research hotspot in ophthalmology. However, current corre...

Comparative Numerical Analysis of Astigmatism Tolerance in Bifocal, Extended Depth-of-Focus, and Trifocal Intraocular Lenses

Numerical Analysis Enhances Postoperative Visual Assessment and Optimization for Multifocal Intraocular Lenses (IOLs) Introduction and Research Background One of the main goals of cataract surgery is to achieve spectacle-free vision for patients. However, this goal is limited by two major challenges: loss of accommodative function and postoperative...

Robotics and Optical Coherence Tomography: Current Works and Future Perspectives

The Combination of Optical Coherence Tomography and Robotics: Current Research and Future Perspectives Academic Background Optical Coherence Tomography (OCT) is a non-invasive, high-resolution optical imaging technique that has been widely used in the field of biomedical imaging since its invention. It provides micrometer-level visualization of tis...

Recording Dynamic Facial Micro-Expressions with a Multi-Focus Camera Array

High-Resolution Dynamic Facial Micro-Expression Capture: Innovations in Multi-Focus Camera Array Background and Research Issues Capturing high-quality dynamic facial images is of critical importance in various fields such as biomedicine, emotion recognition, disease diagnosis, surgical outcome evaluation, facial prosthetic design, and genetic featu...

Development of a Novel Label-Free Functional, Molecular, and Structural Imaging System Combining Optical Coherence Tomography and Raman Spectroscopy for In Vivo Measurement of Rat Retina

Development of a Novel Label-Free Functional, Molecular, and Structural Imaging System Combining Optical Coherence Tomography and Raman Spectroscopy for In Vivo Measurement of Rat Retina

A Revolution in Optical Imaging: Development of a Multimodal Retinal Imaging System Combining OCT and Raman Spectroscopy Research Background and Significance Accessing molecular information of retinal tissue is pivotal for the early diagnosis of ophthalmic and neurodegenerative diseases. However, the current gold standard in retinal imaging—Optical...