Lumped Parameter Simulations of Cervical Lymphatic Vessels: Dynamics of Murine Cerebrospinal Fluid Efflux from the Skull

Physics, Fluid Physics, Engineering, Mechanical Engineering, Medicine, Neurology,
cervical lymphatic vessels   lymphatic system   cerebrospinal fluid   traumatic brain injury   numerical simulation   fluid dynamics   intracranial pressure  

Numerical Simulation Study of Cerebrospinal Fluid Drainage through Cervical Lymphatic Vessels Background Introduction Cerebrospinal fluid (CSF) is a clear fluid that circulates around the brain and spinal cord, providing physical protection, nutrient supply, and waste clearance for the central nervous system. In recent years, growing evidence sugge...

Numerical Study of the Effects of Minor Structures and Mean Velocity Fields in the Cerebrospinal Fluid Flow

Physics, Fluid Physics, Engineering, Mechanical Engineering, Medicine, Neurology, Life Sciences, Bioengineering,
cerebrospinal fluid   intrathecal injection   computational fluid dynamics   lagrangian velocity   spinal subarachnoid space   fluid transport   geometric variability  

Study on Cerebrospinal Fluid Flow Dynamics and Its Application in Drug Delivery Background Introduction Cerebrospinal fluid (CSF) plays a crucial role in the human spinal canal, responsible for transporting dissolved nutrients and waste products. Due to its pulsatile nature, CSF flow is influenced by cardiac and respiratory cycles. In recent years,...

Association between Choroid Plexus Volume and Cognitive Function in Community-Dwelling Older Adults without Dementia: A Population-Based Cross-Sectional Analysis

Medicine, Geriatrics, Neurology, Medical Imaging,
choroid plexus   cognitive function   older adults   cerebrospinal fluid   cross-sectional analysis   dementia   brain imaging  

Association Between Choroid Plexus Volume and Cognitive Function in Community-Dwelling Older Adults: A Research Study Academic Background With the increasing global aging population, the number of dementia patients is rising annually. Early identification of older adults with declining cognitive function and guiding them toward preventive and thera...

Fabrication and In Vivo Testing of a Sub-mm Duckbill Valve for Hydrocephalus Treatment

Medicine, Neurology, Neurosurgery, Life Sciences, Bioengineering,
hydrocephalus   duckbill valve   intracranial pressure   cerebrospinal fluid   shunting systems  

Fabrication and In Vivo Testing of a Sub-mm Duckbill Valve for Hydrocephalus Treatment Academic Background Hydrocephalus is a complex pathological condition characterized by the accumulation of cerebrospinal fluid (CSF) in the cranium due to an imbalance between CSF production and absorption. This accumulation leads to increased intracranial pressu...

Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent glioblastoma

Medicine, Rheumatology and Immunology, Neurology, Neurosurgery, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
glioblastoma   tumor microenvironment   single-cell sequencing   Treg cells   cerebrospinal fluid   immunosuppression   tumor biomarkers  

Single-Cell Atlas Reveals Immunosuppressive Microenvironment and Treg Cell Distribution in Recurrent Glioblastoma Glioblastoma is the most aggressive brain tumor, with a very high recurrence rate and poor prognosis. Although many studies have explored the tumor microenvironment of this disease, the understanding of the immune microenvironment in re...

Routine CSF parameters as predictors of disease course in multiple sclerosis: an MSBase cohort study

Medicine, Neurology, Life Sciences, Immunology,
cerebrospinal fluid   multiple sclerosis   prognosis   disability   relapse rate  

Research Report: Predictive Role of Cerebrospinal Fluid Routine Parameters in the Disease Process of Multiple Sclerosis Background Multiple Sclerosis (MS) is characterized by a highly variable and unpredictable disease course. In the diagnosis of MS, cerebrospinal fluid (CSF) analysis is often a standard procedure. However, there has been ongoing d...