Comprehensive Academic Report on Scientific Paper Research Background Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system (CNS), affecting approximately 2.8 million people worldwide. The pathological mechanisms of this disease are mainly related to autoimmune-mediated demyelination and axonal transectio...

Predictive Autoantibody Signature for Multiple Sclerosis Academic Background and Research Significance Multiple Sclerosis (MS) is a chronic inflammatory autoimmune disease that primarily affects the white matter of the central nervous system (CNS). Previous studies have mostly suggested that T cells play a major role in the pathogenesis of MS. Howe...

Alzheimer’s disease (AD) is an age-related chronic neurodegenerative disorder, whose pathological mechanism involves multiple factors, including brain inflammation. Microglia, particularly those expressing the AD risk gene TREM2, are believed to play a crucial role in the development of AD, but their exact contribution has not been fully elucidated...