Enhancing Fall Risk Assessment: Instrumenting Vision with Deep Learning During Walks

Introduction Fall events are common across various clinical populations, with usual risk assessments including visual observation of individual gait. However, gait observation assessments are typically confined to laboratory settings, involving standardized walking protocol tests to identify potential defects that might increase fall risk. Subtle d...

The Ankle Dorsiflexion Kinetics Demand to Increase Swing Phase Foot-Ground Clearance: Implications for Assistive Device Design and Energy Demands

Research Report Background Introduction With an aging population and the increase in neurological and muscular diseases such as stroke, the risk of tripping and falling due to gait disorders has become a serious problem. Research shows that ankle dorsiflexion is crucial for ensuring foot clearance during the swing phase of gait. However, there is l...

Time Synchronization Between Parietal–Frontocentral Connectivity with MRCP and Gait in Post-Stroke Bipedal Tasks

Time Synchronization of Motor-Related Cortical Potentials and Parieto-Frontocentral Connectivity in Bilateral Tasks of Stroke Patients Background In stroke rehabilitation research, functional connectivity (FC), motor-related cortical potentials (MRCP), and gait activities are common metrics related to rehabilitation outcomes. Although these have be...

Inter-alpha-trypsin inhibitor heavy chain h3 is a potential biomarker for disease activity in myasthenia gravis

Research Background Myasthenia Gravis (MG) is a chronic antibody-mediated autoimmune disease that primarily affects synaptic transmission at the neuromuscular junction. Approximately 85% of MG patients are antibody-mediated targeting acetylcholine receptors (AChR). The clinical features of this disease include muscle weakness, especially fatigue-in...

Classifying Neuronal Cell Types Based on Shared Electrophysiological Information from Humans and Mice

Innovative Fusion in Neuron Classification: Shared Information from Human and Mouse Electrophysiological Data The scientific community has long faced significant challenges in neuron classification. Accurate classification of neurons is crucial for understanding brain function in both healthy and diseased states. This study, led by Ofek Ophir, Orit...

Introduction to Cadence: A Neuroinformatics Tool for Supervised Calcium Events Detection

A New Breakthrough in Neuroinformatics: Research Report on Cadence Tool for Calcium Event Detection Background Introduction Calcium imaging technology has revolutionized the study of neuron ensembles, providing researchers with a powerful tool to simultaneously visualize and monitor multiple neuronal activities. Calcium imaging utilizes fluorescent...

Predicting cognitive functioning for patients with a high-grade glioma: Evaluating different representations of tumor location in a common space

Academic Background It is widely recognized that the cognitive function of patients with high-grade glioma is affected by the location and volume of the tumor. However, research on how to accurately predict individual patients’ cognitive function for personalized treatment decisions before and after surgery remains limited. Currently, most studies ...

Bayesian Tensor Modeling for Image-Based Classification of Alzheimer's Disease

Image Classification Based on Bayesian Tensor Modeling for Alzheimer’s Disease Introduction Neuroimaging research is a crucial component of contemporary neuroscience, significantly enhancing our understanding of brain structure and function. Through these non-invasive visualization techniques, researchers can more accurately predict the risk of cer...

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder Using the PED Algorithm

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder Using the PED Algorithm

Identifying Diagnostic Biomarkers for Autism Spectrum Disorder using the PED Algorithm In the field of neuroinformatics, research on Autism Spectrum Disorder (ASD) predominantly focuses on the bidirectional connectivity between brain regions, with fewer studies addressing higher-order interaction anomalies among brain regions. To explore the comple...

Enhanced Spatial Fuzzy C-Means Algorithm for Brain Tissue Segmentation in T1 Images

Research Report on the Enhanced Spatial Fuzzy C-Means Algorithm for Brain Tissue Segmentation Academic Background Magnetic Resonance Imaging (MRI) plays a vital role in neurology, particularly in the precise segmentation of brain tissue. Accurate tissue segmentation is crucial for diagnosing brain injuries and neurodegenerative diseases. Segmenting...