Homeostasis and Metabolism of Iron and Other Metal Ions in Neurodegenerative Diseases

Chemistry, Medicinal Chemistry, Medicine, Neurology, Life Sciences, Biochemistry,
Neurodegenerative Diseases   Metal Ions   Iron   Manganese   Copper   Zinc   Chelators  

Homeostasis and Metabolism of Iron and Other Metal Ions in Neurodegenerative Diseases Academic Background Neurodegenerative diseases (such as Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and Huntington’s disease) are characterized by neuronal death and gradual loss of function, leading to the deterioration of cognitive, ...

Retention of UC-II® Undenatured Type II Collagen During Functional Food and Beverage Prototype Processing

Chemistry, Analytical Chemistry, Chemical Engineering,
undenatured type II collagen   joint health   functional nutrients   foods   beverages   processing stability  

UC-II® Undenatured Type II Collagen Retention in Functional Food and Beverage Processing Academic Background Collagen is widely used in the food and beverage industry to enhance the nutritional and health value of products. Specifically, undenatured type II collagen (UC-II®) has garnered attention for its potential benefits to joint health. However...

Machine Learning and Confirmatory Factor Analysis Show that Buprenorphine Alters Motor and Anxiety-like Behaviors in Male, Female, and Obese C57BL/6J Mice

Chemistry, Medicinal Chemistry, Medicine, Psychiatry, Neurology, Life Sciences, Biochemistry,
Buprenorphine   Machine Learning   Confirmatory Factor Analysis   Motor Behavior   Anxiety-like Behavior   C57BL/6J Mice   Obesity  

In recent years, with the global increase in drug abuse, particularly opioids, scientists have become increasingly focused on the neurobehavioral effects of such substances. Among them, buprenorphine, an opioid, is widely used for medication-assisted treatment of opioid addiction. However, beyond its analgesic and addiction treatment effects, bupre...

Multi-Task Aquatic Toxicity Prediction Model Based on Multi-Level Features Fusion

Chemistry, Computational Chemistry, Environmental Chemistry, Engineering, Environmental Engineering, Information Science, Computer Science, Artificial Intelligence, Medicine, Environmental and Public Health,
aquatic toxicity   deep learning   multi-task model   molecular fingerprints   molecular graph features  

Academic Background With the growing threat of organic compounds to environmental pollution, studying the toxic responses of different aquatic organisms to these compounds has become crucial. Such research not only helps assess the potential ecological impacts of pollutants on the overall aquatic ecosystem but also provides significant scientific f...

Hybridization-Based Discovery of Novel Quinazoline-2-Indolinone Derivatives as Potent and Selective PI3Kα Inhibitors

Chemistry, Medicinal Chemistry, Medicine, Pharmacy, Oncology,
molecular hybridization   quinazoline   2-indolinone   PI3Kα inhibitor   non-small cell lung cancer  

Research and Development of a Novel PI3Kα Inhibitor: Molecular Hybridization Technology Leads to a Breakthrough in Lung Cancer Treatment Academic Background Cancer, particularly non-small cell lung cancer (NSCLC), is the second leading cause of death worldwide. Currently, chemotherapy is the primary treatment method, but due to its lack of targetin...

High Performance of Functionalized Carbon Dots in the Detection of Dye Contaminants

Chemistry, Analytical Chemistry, Physical Chemistry, Materials Science,
Surface Enhanced Raman Scattering   Carbon Dots   Charge Transfer   Mg Detection   Environmental Monitoring   Food Safety   Nanocomposites  

High-Performance SERS Detection of Dye Contaminants Using Novel Functionalized Carbon Dots Academic Background Dye molecules play a vital role in daily life, but the environmental pollution caused by their use cannot be ignored. Among them, Malachite Green (MG) is a triphenylmethane dye with potential carcinogenic, teratogenic, and mutagenic effect...

Metal-Free Production of Natural Blue Colorants through Anthocyanin-Protein Interactions

Chemistry, Analytical Chemistry, Physical Chemistry, Life Sciences, Biochemistry,
Natural blue colorants   Anthocyanins   Protein interactions   Metal-free production   Food additives  

Metal-Free Production of Natural Blue Colorants: Novel Insights from Anthocyanin-Protein Interactions Academic Background With increasing consumer awareness of health and natural food ingredients, the demand for natural colorants has been on the rise. However, natural blue colorants are scarce, and their production poses significant challenges. Cur...

Flexible No-Drift Data Glove Using Ultrathin Silicon for the Metaverse

Chemistry, Nanoscience, Materials Science, Metallic Materials, Information Science, Semiconductors and Information Devices,
no-drift sensor   ultrathin silicon   data glove   human-machine interface   metaverse  

Academic Background With the rapid development of the Metaverse, human-machine interface (HMI) technology has become a key link between virtual space and human users. Among these, gesture recognition technology is particularly important in the Metaverse, especially the precise capture of finger movements. Traditional bending sensors used for gestur...

Ultralow-Power Carbon Dioxide Sensor for Real-Time Breath Monitoring

Chemistry, Nanoscience, Engineering, Electrical Engineering, Materials Science, Medicine, Respiratory System, Life Sciences, Bioengineering,
carbon dioxide sensor   breath monitoring   optochemical sensor   low power consumption   real-time monitoring  

Research on an Ultra-Low Power Carbon Dioxide Sensor for Real-Time Breath Monitoring Academic Background Carbon dioxide (CO₂) is a critical gas produced during human respiration, and its real-time monitoring is essential for diagnosing and treating respiratory diseases (e.g., asthma, dyspnea, sleep apnea) as well as metabolic disorders. Traditional...

Pressure Effects on Lithium Anode/Nickel-Manganese-Cobalt Oxide Cathode Pouch Cells Through Fixture Design

Chemistry, Energy Chemistry, Chemical Engineering, Engineering, Energy Engineering, Materials Science,
lithium metal batteries   pouch cells   external pressure   fixture design   battery performance   cycle life   electrolyte  

Pressure Effects in Lithium-Metal Batteries: Optimizing Battery Performance through Fixture Design Academic Background With the rapid development of electric vehicles (EVs) and renewable energy, the demand for high-energy-density batteries is increasing. Lithium-metal batteries are considered strong candidates for next-generation battery technology...