Research Report: Feasibility Study of Intracranial Focused Ultrasound Ablation under Ultrasonic Guidance through Polyolefin-Based Cranial Implants Academic Background Histotripsy is a non-thermal, non-invasive cancer tumor ablation technology. When applied intracranially, it is limited by the skull’s significant absorption and reflection of ultraso...

Space-Specific Mixed Excitation Technique for High Signal-to-Noise Ratio Spatial Encoding in Magnetic Particle Imaging Background Introduction Magnetic Particle Imaging (MPI) is an emerging, radiation-free tracer imaging technology that visualizes the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs) to achieve high-sensiti...

Piezo1 and Piezo2 Mechanosensitive Ion Channels Regulate the Response of Rodents to Transcranial Focused Ultrasound Stimulation of the Motor Cortex Academic Background Transcranial Focused Ultrasound (TFUS) neuromodulation is a non-invasive, deep brain stimulation technique that shows great potential in the study of neural circuits and the treatmen...

Academic News Report: Study on the Optical Transmission Characteristics of Cartilage Introduction Cartilage is a complex biological tissue composed of cells and a substantial extracellular matrix. Its main components include collagen fibers, proteoglycans, and water, which form layered structural partitions at the microscopic level. The propagation...

Background and Research Motivation Parkinson’s Disease (PD) is a neurodegenerative disorder primarily affecting patients’ motor abilities, leading to tremors, bradykinesia, limb rigidity, and problems with gait and balance. These motor deficits significantly impact patients’ ability to live independently and their quality of life. Statistics predic...

Prediction of Ventricular Fibrillation in Myocardial Infarction Model in Pigs Based on T-peak-to-T-end Interval Variation Using Time Warping Technique Background Introduction Source of the Paper Sudden Cardiac Death (SCD) is a leading cause of mortality worldwide, with one of its primary pathogenic mechanisms being Ventricular Fibrillation (VF), es...

Academic News Report: New MRI Technology Achieves Biological Fluorescence Imaging by Detecting Local Hemodynamics of Photosensitive Blood Vessels Academic Background Introduction Bioluminescent probes are widely used for monitoring biomedical processes and cellular targets in living animals. However, the absorption and scattering of visible light b...

Insights into the Association Between Sleep and Mortality Revealed by Self-supervised Learning of Wrist-worn Accelerometer Data In modern society, sleep is an essential basic activity for life, and its importance is self-evident. Accurately measuring and classifying sleep/wake states and different sleep stages is crucial for diagnosing sleep disord...

Development and Validation of Large-Scale Machine Learning Algorithms for Cardiovascular Diagnosis Based on Electrocardiograms Introduction Cardiovascular diseases (CV) have long been a major source of global disease burden. Early diagnosis and intervention are crucial for reducing complications, healthcare utilization, and associated costs. Tradit...

MRI-Guided Staged Bilateral Focused Ultrasound Subthalamotomy for Parkinson’s Disease Background Parkinson’s Disease (PD) is a common neurodegenerative disorder, characterized mainly by motor symptoms such as tremor, rigidity, and bradykinesia. Traditionally, treatments for PD include medication and surgical interventions such as Deep Brain Stimula...