The Cortical Neurophysiological Signature of Amyotrophic Lateral Sclerosis

Analysis of Cortical Neurophysiological Characteristics of ALS and Its Potential as a Biomarker Background Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects adults, characterized by a gradual loss of the integrity of the brain, spinal cord, and peripheral motor system. Although clinical and genetic studies have reveale...

Negation Mitigates Rather Than Inverts the Neural Representations of Adjectives

Background Introduction A notable characteristic of human language processing is our ability to combine stored lexical elements, i.e., words, as needed to flexibly generate or alter current meanings. At the core of this process is how we construct semantic representations in real time. Although research on the generation of syntactic structures has...

Phase-dependent word perception emerges from region-specific sensitivity to the statistics of language

Phase-dependent word perception emerges from region-specific sensitivity to the statistics of language

Phase-Dependent Language Perception in Neural Oscillations: An Interdisciplinary Study Report Background During speech perception, the phase of neural oscillations plays a crucial role in the separation of neural representations and perceptual decisions. However, the specific phase-encoding mechanisms remain unclear. This study aims to reveal how p...

Reactivation strength during cued recall is modulated by graph distance within cognitive maps

Reactivation Strength in Memory is Modulated by Graph Distance in Cognitive Maps Research Background Memory formation and retrieval are among the crucial areas of research in neuroscience. Classic memory theories propose that memory depends on three distinct stages: encoding, consolidation, and retrieval. New episodic memories are formed through en...

Somatosensory Evoked Spikes in Normal Adults Detected by Magnetoencephalography

Somatosensory Evoked Spikes in Normal Adults Detected by Magnetoencephalography Research Background and Motivation Since 1949, clinical neurophysiology research has discovered that high-voltage cortical somatosensory evoked potentials (SEPs) can be detected in patients with reflex epilepsy, where seizures are triggered by somatosensory stimulation ...

Spatiotemporal Brain Hierarchies of Auditory Memory Recognition and Predictive Coding

Spatiotemporal Brain Hierarchies of Auditory Memory Recognition and Predictive Coding

The Spatiotemporal Hierarchical Structure of the Brain in Auditory Memory Recognition and Predictive Coding Background This study aims to explore the hierarchical brain mechanisms involved in human identification of previously memorized music sequences and their systematic changes. While extensive research has been conducted on neural processing of...

Post-Task Responses Following Working Memory and Movement Are Driven by Transient Spectral Bursts with Similar Characteristics

Background and Research Questions Working memory and post-task responses (PTRs) in the brain have been a focal point in neuroscience research. Previous studies have shown that post-movement beta rebound (PMBR) is a reliable and stable phenomenon in the cerebral cortex that can be studied and measured using magnetoencephalography (MEG). Recent resea...

Human Sensorimotor Resting State Beta Events and Aperiodic Activity Show Good Test–Retest Reliability

Human Sensorimotor Resting State β Events and Aperiodic Activity Exhibit Good Test-Retest Reliability Background Neurological diseases are some of the most impactful diseases on daily human life, particularly those affecting sensory and motor functions, such as Parkinson’s disease. Early diagnosis of these diseases is often exceedingly difficult du...

Spatiotemporal Dynamics of Cortical Somatosensory Network in Typically Developing Children

Temporal and Spatial Dynamics of Somatosensory Cortex Network in Typically Developing Children Research Background Touch plays a crucial role in our interaction with external objects and the fine control of hand movements. Despite substantial research on the mechanisms of sensory information processing in human skin, it remains unclear how brain re...

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Measurement of Human Auditory Evoked Fields Using a Flexible Multichannel Optically Pumped Magnetometer MEG System Xin Zhang and others, from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences, University of Science and Technology of China, Jihua Laboratory in Foshan, Guangdong Province, and Guoke Medic...