Investigating Useful Features for Overall Survival Prediction in Patients with Low-Grade Glioma Using Histology Slides

Useful Features for Overall Survival Prediction in Low-Grade Glioma Patients Academic Background Glioma is a type of neoplastic growth in the brain that usually poses a serious threat to the patients’ lives. In most cases, glioma eventually leads to the death of the patient. The analysis of glioma typically involves examining pathological slices of...

Gliomas Disease Prediction: An Optimized Ensemble Machine Learning-Based Approach

Glioma Disease Prediction Based on Optimized Integrated Machine Learning Background and Research Objectives In medical research, gliomas are the most common type of primary brain tumors, encompassing various cancer types with different clinical behaviors and treatment outcomes. Accurate prognosis prediction for glioma patients is crucial for optimi...

Empowering Glioma Prognosis with Transparent Machine Learning and Interpretative Insights Using Explainable AI

Enabling Explainable Artificial Intelligence for Glioma Prognosis: Translational Insights from Transparent Machine Learning Academic Background This study is dedicated to developing a reliable technique to detect whether patients have a specific type of brain tumor—glioma—using various machine learning methods and deep learning methods, combined wi...

Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

Clinical Validation Study on the Application of Cell-Free DNA Fragment Analysis in Enhancing Early Detection of Lung Cancer Background Lung cancer is one of the leading types of cancer threatening the health of both men and women globally. Over 125,000 people die from lung cancer in the United States each year, and globally, the number is close to ...

Asthma Prediction via Affinity Graph Enhanced Classifier: A Machine Learning Approach Based on Routine Blood Biomarkers

Asthma Prediction Enhanced by Affinity Graph-Based Classifier: A Machine Learning Approach Using Routine Blood Biomarkers Background Asthma is a chronic respiratory disease that affects approximately 235 million people worldwide. According to the World Health Organization (WHO), the main characteristic of asthma is airway inflammation, leading to s...

Investigation of the Impact of Cross-Frequency Coupling on the Assessment of Depression Severity through the Analysis of Resting State EEG Signals

Background Depression, particularly Major Depressive Disorder (MDD), is a widespread and debilitating psychological disease often described as the “common cold” of mental health. Many people with MDD experience symptoms such as persistent sadness, hopelessness, cognitive impairment, and loss of motivation for daily activities, severely affecting pe...

Distinguishing Parkinsonian Rest Tremor from Voluntary Hand Movements through Subthalamic and Cortical Activity

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized mainly by resting tremor, bradykinesia, and rigidity. Deep Brain Stimulation (DBS) has been widely used to treat the motor symptoms of PD (Krauss et al., 2021). However, DBS treatment also has significant side effects, most of which are caused by the extension of stimulat...

The Role of EEG Microstates in Predicting Oxcarbazepine Treatment Outcomes in Patients with Newly-Diagnosed Focal Epilepsy

The Role of EEG Microstates in Predicting Oxcarbazepine Treatment Outcomes in Patients with Newly-Diagnosed Focal Epilepsy

The Role of EEG Microstates in Predicting the Therapeutic Outcomes of Oxcarbazepine in Newly Diagnosed Focal Epilepsy Patients Introduction Background Focal epilepsy is the most common type of epilepsy, accounting for about 60% of all epilepsy cases. The selection of antiepileptic drugs (AEDs) varies depending on the type of epilepsy. In the treatm...

Deep Learning-Based Assessment Model for Real-Time Identification of Visual Learners Using Raw EEG

In the current educational environment, understanding students’ learning styles is crucial for improving their learning efficiency. Specifically, the identification of visual learning styles can help teachers and students adopt more effective strategies in the teaching and learning process. Currently, automatic identification of visual learning sty...

Magnetoencephalography-Derived Oscillatory Microstate Patterns Across Lifespan: The Cambridge Centre for Ageing and Neuroscience Cohort

Application of Magnetoencephalography (MEG) to Analyze Changes in Whole-Brain Oscillatory Microstate Patterns Across the Lifespan: Cambridge Centre for Aging and Neuroscience Cohort Study Research Background With the increasing seriousness of the aging population problem, understanding the neurophysiological changes during the aging process becomes...