Analysis of Cerebral CT Based on Supervised Machine Learning as a Predictor of Outcome After Out-of-Hospital Cardiac Arrest

Brain CT Analysis as a Tool for Outcome Prediction after Out-of-Hospital Cardiac Arrest: A Supervised Machine Learning Analysis Research Background Out-of-Hospital Cardiac Arrest (OHCA) is one of the leading causes of death in the Western world, with extremely low survival rates, ranging from 3% to 16%. The neurological and overall outcomes after O...

Radiomics-based Prediction of Local Control in Patients with Brain Metastases Following Postoperative Stereotactic Radiotherapy

Application of Radiomics in Predicting Local Control in Postoperative Stereotactic Radiotherapy for Brain Metastasis Patients Academic Background Brain Metastases (BMs) are the most common malignant brain tumors, far surpassing primary brain tumors like gliomas in incidence. Recent medical guidelines recommend surgical treatment for patients with s...

Raman-Based Machine Learning Platform Reveals Unique Metabolic Differences Between IDHmut and IDHwt Glioma

Study on Metabolic Differences between IDH Mutant and Wild-type Glioma Cells Using Raman Spectroscopy and Machine Learning Platform Background Introduction In the diagnosis and treatment of gliomas, formalin-fixed, paraffin-embedded (FFPE) tissue sections are commonly used. However, due to background noise interference from the embedding medium, th...

A Novel CNN-Based Image Segmentation Pipeline for Individualized Feline Spinal Cord Stimulation Modeling

Automated Spinal Cord Segmentation Pipeline Based on Convolutional Neural Network (CNN) for Individualized Cat Spinal Cord Stimulation Modeling Background and Research Motivation Spinal cord stimulation (SCS) is a widely used treatment method for chronic pain management. In recent years, it has also been used to modulate neural activity, aiming to ...

Accelerating Ionizable Lipid Discovery for mRNA Delivery Using Machine Learning and Combinatorial Chemistry

Accelerating the Discovery of Ionizable Lipids for mRNA Delivery using Machine Learning and Combinatorial Chemistry Research Background To fully realize the potential of mRNA therapies, it is essential to expand the toolkit of lipid nanoparticles (LNPs). However, a key bottleneck in LNP development is identifying new ionizable lipids. Previous stud...

Sequential Safe Static and Dynamic Screening Rule for Accelerating Support Tensor Machine

With the continuous advancement of data acquisition technology, obtaining large amounts of high-dimensional data containing multiple features has become very easy, such as images and vision data. However, traditional machine learning methods, especially those based on vectors and matrices, face challenges such as the curse of dimensionality, increa...

Learning Robust Autonomous Navigation and Locomotion for Wheeled-Legged Robots

Learning Robust Autonomous Navigation and Locomotion for Wheeled-Legged Robots

Autonomous Navigation and Walking Wheel-Leg Robot Background Introduction The acceleration of urbanization has posed significant challenges for supply chain logistics, especially for last-mile delivery. As traffic pressure increases and the demand for faster delivery services rises, particularly with complex routes indoors and on city streets, trad...

Comprehensive Peripheral Blood Immunoprofiling Reveals Five Immunotypes with Immunotherapy Response Characteristics in Patients with Cancer

Research Report on the Analysis of Immunological Characteristics of Peripheral Blood in Cancer Patients Cancer is a major and pervasive health problem globally. Despite significant advances in cancer treatment in recent years, many challenges remain, including how to accurately predict patients’ responses to various treatments. Immunotherapy, parti...

Quantification and Diagnosis of Mobility Deficits

Background and Research Motivation Parkinson’s Disease (PD) is a neurodegenerative disorder primarily affecting patients’ motor abilities, leading to tremors, bradykinesia, limb rigidity, and problems with gait and balance. These motor deficits significantly impact patients’ ability to live independently and their quality of life. Statistics predic...

Strokeclassifier: Ischemic Stroke Etiology Classification by Ensemble Consensus Modeling Using Electronic Health Records

StrokeClassifier: An AI Tool for Etiological Classification of Ischemic Stroke Based on Electronic Health Records Project Background and Motivation Identifying the etiology of strokes, particularly acute ischemic stroke (AIS), is crucial for secondary prevention, but it is often very challenging. In the United States, there are nearly 676,000 new c...