Exploring Biomarkers and Biosensors for Motion Sickness: Innovative Approaches to Diagnostic Challenges Motion sickness (MS) is a common syndrome experienced by humans, triggered by unnatural motions such as those encountered during transportation or virtual reality (VR). It manifests through symptoms like headaches, nausea, vomiting, cold sweats, ...
Choline Phosphate-Based Antigen Capture Strategy Boosts In Situ Tumor Vaccine Research: A Novel Immunotherapy Approach In the field of cancer immunotherapy, in situ tumor vaccines have garnered significant attention for their ability to harness a patient’s immune system to target tumors. However, challenges remain in their clinical application. To ...
Mitochondria-Targeting Bimetallic Cluster Nanozymes Alleviate Neuropathic Pain by Scavenging ROS and Reducing Inflammation Background Introduction Neuropathic pain is a complex and multifaceted public health issue, with its high incidence and significant negative impact on patients’ quality of life making it a critical area of medical research. Cur...
Preference Prediction-Based Evolutionary Multiobjective Optimization for Gasoline Blending Scheduling Background Introduction With the continuous evolution of the global energy market, gasoline production and blending processes face increasing challenges. As a key product of the oil industry, gasoline’s blending and scheduling processes directly af...
Dual Ferroptosis Induction via FTH1 Targeting: A New Therapeutic Strategy for Triple-Negative Breast Cancer (TNBC) Background: Why Conduct This Study? Breast cancer is one of the most common cancer types worldwide, accounting for 11.7% of all new cancer cases globally. Among its several subtypes, triple-negative breast cancer (TNBC) stands out for ...
Research on a New Platform for Tumor-Specific Drug Delivery Targeting the Warburg Effect Cancer remains a global health challenge. Traditional cancer treatments, such as chemotherapy and radiotherapy, often come with significant side effects due to their inability to distinguish between tumor tissues and healthy tissues, leading to damage in the la...
Research Report: Mitochondrial Uncouplers Inhibit E2F1 Activity and Prostate Cancer Growth Background Prostate cancer (PC) is the most common cancer and the second leading cause of cancer-related deaths among men in the United States. In 2024, an estimated 299,010 American men will be diagnosed with prostate cancer, and 35,250 will die from the dis...
Protein-Functionalized and Intrinsically Radiolabeled [188Re]ReOx Nanoparticles: Breakthrough Application in Multimodal Synergistic Cancer Therapy Cancer remains one of the leading causes of death globally, despite significant progress in medical science over the past few decades. However, early detection and treatment methods still face significan...
Distinguishing Novel Sandwich-Type Tungsten Oxide Cluster Compounds Using Two-Dimensional Correlation Infrared Spectroscopy Background Introduction Polyoxometalates (POMs) are metal-oxygen cluster compounds linked through oxygen coordination with transition metal ions. They play significant roles in catalysis, optics, medicine, and magnetism. Howev...
Background and Research Questions Atomic gold nanoclusters (AuNCs), with particle sizes typically not exceeding 2 nanometers, have garnered extensive attention in recent years due to their unique photophysical properties, making them highly advantageous in biomedicine, catalysis, and sensing. These properties include excellent catalytic activity, t...