Development of a Molecular Probe for Tumor-Associated Protein Mesothelin Based on PET Imaging Technology Research Background In recent years, mesothelin (MSLN) has become a key focus in cancer research and diagnostics. Mesothelin is a membrane-bound glycoprotein highly expressed on the surface of various malignancies, including ovarian, pancreatic,...
Revealing Gene Expression Patterns Associated with Synaptic Density Network Dysfunction in Temporal Lobe Epilepsy Background Temporal Lobe Epilepsy (TLE) is the most common form of focal epilepsy, and its pathological features and mechanisms have long drawn extensive attention in the field of neuroscience. This disorder involves not only a single b...
REF-1 Overexpression in Neovascular Eye Diseases and Therapeutic Targeting with a Novel Inhibitor Academic Background Neovascular age-related macular degeneration (nAMD) is a common blinding eye disease predominantly affecting individuals aged 60 years and older. nAMD is characterized by the formation of subretinal neovascularization, leading to re...
Background With the widespread adoption of cataract surgery and lens replacement surgery, the optical performance of intraocular lenses (IOLs) has become increasingly critical in determining patients’ postoperative visual quality. Predicting clinical visual performance (such as visual acuity and defocus range) is an emerging area of interest in oph...
Study on Three-Dimensional Monitoring of Red Blood Cell Sedimentation under External Magnetic Fields: A Novel Scientific Perspective Background and Research Objective With the widespread use of electronic devices in modern society, humans are increasingly exposed to external magnetic fields (MFs) in their living environments. However, the potential...
Research Advances on a Novel Compact Double-Pass Intraocular Scatter Measurement System Academic Background According to the World Health Organization (WHO), cataracts are the leading cause of blindness globally, accounting for approximately 50% of all blindness cases. More than 20 million people worldwide suffer from vision loss or severe impairme...
Polarimetric Imaging Technology Assisting Intraoperative Peripheral Nerve Identification: A Cutting-Edge Study Peripheral nerves play a crucial role in the sensory and control networks of the human body, and their integrity and proper functioning are essential to our quality of life. Unfortunately, accidental peripheral nerve injuries are not uncom...
Challenging Skin Pigmentation Bias: Application of Time-Domain Near-Infrared Spectroscopy in Tissue Oximetry Background and Motivation In recent years, optical technologies have been increasingly utilized in medical diagnostics and therapies. However, varying levels of skin pigmentation (which depend on melanin concentration in the skin) can signif...
Demonstration of Femtosecond Laser Induced Refractive Index Change in Silk-Fibroin Hydrogels: A New Hope for Future Ophthalmic Biocompatible Implants In today’s era of advanced biotechnology and rapid developments in the biomedical field, refractive correction techniques have become a global research hotspot in ophthalmology. However, current corre...
The Combination of Optical Coherence Tomography and Robotics: Current Research and Future Perspectives Academic Background Optical Coherence Tomography (OCT) is a non-invasive, high-resolution optical imaging technique that has been widely used in the field of biomedical imaging since its invention. It provides micrometer-level visualization of tis...