A Neurofunctional Study of Tactile Feedback in Stroke Rehabilitation Based on fNIRS Academic Background Stroke is a common neurological condition that profoundly affects patients’ daily lives and quality of life. Among the various functional impairments caused by stroke, hand dysfunction is particularly notable, manifesting in decreased muscle stre...
A Revolution in Optical Imaging: Development of a Multimodal Retinal Imaging System Combining OCT and Raman Spectroscopy Research Background and Significance Accessing molecular information of retinal tissue is pivotal for the early diagnosis of ophthalmic and neurodegenerative diseases. However, the current gold standard in retinal imaging—Optical...
Exploring the Potential of Fiber Optic Sagnac Interferometer in Non-Contact Elasticity Characterization of Soft Tissues Introduction The mechanical properties of soft tissues are critical to modern medicine and biomedical research. Understanding these properties provides significant insights into structural integrity and potential pathological cond...
A New Method for Estimating Heart Rate and Respiratory Rate from Videos Background and Research Motivation Heart rate (HR) and respiratory rate (RR) are critical physiological parameters reflecting cardiorespiratory functions. These metrics are widely used in medical, health monitoring, and psychological and behavioral studies. Traditionally, these...
Research Report on Automated Robotic Craniotomy Surgery System Background As the central organ of complex life activities, the brain governs all psychological and conscious processes, playing a crucial role in every aspect of life. Entering the 21st century, neuroscience has become one of the fastest-growing and most prominent fields, with animal m...
Development of Next-Generation Low-Cost Optical Coherence Tomography (OCT) Systems: Advancing Retinal Imaging for Clinical Applications Academic Background Optical Coherence Tomography (OCT) is a non-invasive, high-resolution imaging technology widely used in ophthalmology, particularly for diagnosing retinal diseases. However, existing commercial ...
A New Chapter in the Molecular Understanding of the Human Placenta: Breakthroughs in Spatial Multiomics Background and Research Questions The placenta is the first fetal organ to develop during human pregnancy and plays a critical role in ensuring successful gestation and healthy fetal development. Despite its importance, our understanding of the m...
Gene-level Single-cell Trajectory Alignment: A New Method Based on Dynamic Programming The advent of single-cell RNA sequencing (scRNA-seq) technology has dramatically advanced biological research, enabling scientists to observe dynamic changes at the single-cell level over time and space. However, comparing such dynamics across samples or conditio...
Single-Cell and Spatially Resolved Interactomics of Tooth-Associated Keratinocytes: Exploring the Role of Structural Immunity in Periodontitis Background Periodontitis is a chronic inflammatory disease that affects the periodontal tissues and impacts billions of people globally, potentially resulting in tooth loss. It is primarily caused by polybac...
Super-Resolution Imaging Reveals New Advances in Neural Morphodynamics in Mouse Brains: Dynamic Observations in Head-Fixed Awake Animals Background In the field of neuroscience, understanding the morphological changes and functional dynamics of neurons is key to deciphering how the brain processes information and sustains network plasticity. Despit...