Academic Background and Research Motivation In the field of dental healthcare, Cone Beam Computed Tomography (CBCT) is a widely used three-dimensional imaging technique. CBCT provides three-dimensional images of the oral cavity and is particularly effective in diagnosing odontogenic lesions. However, the segmentation of CBCT images—labeling each vo...

Breakthrough in Next-Generation Oral Ulcer Management: Integration of Cold Plasma and Nanogel Pharmaceutical Systems Background Oral ulcers are one of the most common mucosal diseases, significantly affecting patients’ quality of life. According to epidemiological data, approximately 27.9% of adults suffer from oral ulcers. While these lesions ofte...

A Review on Novel Periodontal Functional Materials: Comprehensive Exploration of Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies Academic Background and Research Significance With the accelerating trend of global population aging, the concern for oral health issues is increasing. Periodontitis, as a common bacterial infectious ...

Single-Cell and Spatially Resolved Interactomics of Tooth-Associated Keratinocytes: Exploring the Role of Structural Immunity in Periodontitis Background Periodontitis is a chronic inflammatory disease that affects the periodontal tissues and impacts billions of people globally, potentially resulting in tooth loss. It is primarily caused by polybac...

Identification of Nanaomycin A and Its Analogs as Functional Inhibitors of the Type IX Secretion System in Porphyromonas gingivalis Using a Novel Screening Method Academic Background Porphyromonas gingivalis is a Gram-negative anaerobic bacterium recognized as one of the primary pathogens in chronic periodontitis. Beyond periodontal diseases, P. gi...

Application of LBL Coatings in the Treatment of Dental Implant-Related Infections Background Dental implant-related infections, particularly peri-implantitis, are inflammatory diseases caused by bacterial biofilms, leading to progressive destruction of surrounding tissues. Peri-implantitis not only may result in implant loss but also can trigger mo...

Unlocking Osseointegration—Surface Engineering Strategies for Enhanced Dental Implant Integration Academic Background Tooth loss is a prevalent issue faced by individuals of all ages worldwide. Dental implants, as a primary means of replacing missing teeth, depend largely on the speed and quality of osseointegration. Osseointegration refers to the ...

“PITX2 Expression and Neanderthal Introgression in HS3ST3A1 Contribute to Variation in Tooth Dimensions in Modern Humans” Source of the Research This paper was authored by Qing Li, Pierre Faux, Emma Wentworth Winchester, and others, and published on January 6, 2025, in the journal Current Biology. The authors come from various research institutions...

Academic Paper Report Caries is one of the most common chronic diseases in children, with significant health disparities across racial, ethnic, and income groups. Despite the availability of effective preventive measures, children from low-income and minority ethnic groups continue to face higher risks of caries. The American Academy of Pediatrics ...

Research Report: Validation and Analysis of a Prognostic Model for Oral Squamous Cell Carcinoma Constructed with TLS-Related Genes Background and Research Motivation Oral Squamous Cell Carcinoma (OSCC) is the most common subtype of Head and Neck Squamous Cell Carcinoma (HNSCC), exhibiting a high tendency for lymph node metastasis, especially to the...