Identification and Validation of a Prognostic Model Based on Three TLS-Related Genes in Oral Squamous Cell Carcinoma

Medicine, Oral Sciences, Medical Imaging, Oncology, Life Sciences, Biochemistry, Immunology, Genetics,
oral squamous cell carcinoma   tertiary lymphoid structure   prognostic model   immune infiltration   convolutional neural network  

Research Report: Validation and Analysis of a Prognostic Model for Oral Squamous Cell Carcinoma Constructed with TLS-Related Genes Background and Research Motivation Oral Squamous Cell Carcinoma (OSCC) is the most common subtype of Head and Neck Squamous Cell Carcinoma (HNSCC), exhibiting a high tendency for lymph node metastasis, especially to the...

Neural Landscape is Associated with Functional Outcomes in Irradiated Patients with Oropharyngeal Squamous Cell Carcinoma

Medicine, Oral Sciences, Neurology, Neurosurgery, Medical Imaging, Oncology, Life Sciences, Immunology,
Neural landscape   Radiation therapy   Oropharyngeal squamous cell carcinoma   Dysphagia   Neuronal changes   Quality improvement   Functional outcomes  

Research on the Association between Neural Networks and Functional Outcomes in Radiotherapy Patients with Pharyngeal Cancer 1. Paper Background Introduction The incidence of human papillomavirus (HPV)-mediated oropharyngeal squamous cell carcinoma (OPSCC) has significantly increased over the past 40 years, especially among younger populations with ...

Loss of TBC1D2B Causes a Progressive Neurological Disorder with Gingival Overgrowth

Medicine, Oral Sciences, Neurology, Life Sciences, Cell Biology, Biochemistry, Genetics,
TBC1D2B gene   neurological disorder   gingival overgrowth   genetic syndrome   autophagy defect   neurodegenerative disease  

Progressive neurological disease with gingival hyperplasia due to TBC1D2B gene deficiency Background Introduction In recent years, with the rapid development of genomic technologies, scientists have gained deeper insights into the relationship between genetic variations and human diseases. Increasingly, research has revealed the important role thes...

Schwann cell derived pleiotrophin stimulates fibroblast proliferation and excessive collagen deposition in plexiform neurofibroma

Medicine, Medical Laboratory Science, Oral Sciences, Neurology, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
Schwann cells   pleiotrophin   fibroblasts   plexiform neurofibroma   collagen deposition   signaling pathway  

This study explores the interactions between Schwann cells and fibroblasts in neurofibromatosis type 1 (NF1) related plexiform neurofibroma (PNF). The background of the research is based on the high incidence of NF1, which affects about 1 in 3000 newborns worldwide and is associated with a series of unique clinical manifestations. PNF is a common p...