Quantification and Diagnosis of Mobility Deficits

Background and Research Motivation Parkinson’s Disease (PD) is a neurodegenerative disorder primarily affecting patients’ motor abilities, leading to tremors, bradykinesia, limb rigidity, and problems with gait and balance. These motor deficits significantly impact patients’ ability to live independently and their quality of life. Statistics predic...

Hybrid Hydrogel-Magnet Actuated Capsule for Automatic Gut Microbiome Sampling

Hybrid Hydrogel-Magnet Actuated Capsule for Automatic Gut Microbiome Sampling

Hybrid Hydrogel-Magnetic Driven Capsule for Automatic Intestinal Microbiome Sampling Academic Background The gut microbiome is composed of a large and diverse community of microorganisms that significantly impact human health, including conditions such as cancer, diabetes, and inflammatory bowel disease (IBD). Current methods for studying the gut m...

T-Wave Peak-to-End Changes Quantified by Time-Warping Predicts Ventricular Fibrillation in a Porcine Myocardial Infarction Model

Prediction of Ventricular Fibrillation in Myocardial Infarction Model in Pigs Based on T-peak-to-T-end Interval Variation Using Time Warping Technique Background Introduction Source of the Paper Sudden Cardiac Death (SCD) is a leading cause of mortality worldwide, with one of its primary pathogenic mechanisms being Ventricular Fibrillation (VF), es...

A Biomimetic Visual Detection Model: Event-Driven LGMDs Implemented with Fractional Spiking Neuron Circuits

A Biomimetic Visual Detection Model: Event-Driven LGMDs Implemented with Fractional Spiking Neuron Circuits

Academic Report: Research on a Biomimetic Visual Detection Model Based on Fractional Spiking Neuron Circuits In the fields of intelligent autonomous driving and unmanned aerial vehicles, quickly and effectively predicting collisions and triggering avoidance behaviors have significant application value. The Lobula Giant Movement Detectors (LGMDs) in...

A Cervical Elastography System Based on Transvaginal Ultrasound Imaging

A Method for Quantifying Cervical Elasticity During Pregnancy Based on Transvaginal Ultrasound and Pressure Measurement Background and Motivation Preterm birth (delivery before 37 weeks of gestation) is a major cause of neonatal morbidity and mortality. Due to the high risks associated with preterm birth, many pregnant women with preterm symptoms n...

Dendritic-Cell-Targeting Virus-Like Particles as Potent mRNA Vaccine Carriers

Dendritic-cell-targeting Virus-like Particles as Potent mRNA Vaccine Carriers Introduction In vaccine development, especially mRNA vaccines, significant achievements have been made in recent years. The mRNA vaccines developed by Moderna and Pfizer/BioNTech against COVID-19 have set a successful precedent, greatly advancing the development of mRNA v...

A bilingual speech neuroprosthesis driven by cortical articulatory representations shared between languages

Bilingual Speech Neuroprosthesis Driven by Cortical Speech Representations Background In the development of neuroprostheses, research on decoding language from brain activity has primarily focused on decoding a single language. Thus, the extent to which bilingual speech production relies on unique or shared cortical activity between different langu...

Antibody-Displaying Extracellular Vesicles for Targeted Cancer Therapy

Antibody-Displaying Extracellular Vesicles for Targeted Cancer Therapy

The Application of Antibodies Displaying Extracellular Vesicles in Targeted Cancer Therapy Extracellular Vesicles (EVs) have been extensively researched as natural delivery carriers and mediators of biological signals in various tissues. In this study, researchers utilized these characteristics of EVs to demonstrate a modular delivery system for ca...

Imaging Bioluminescence by Detecting Localized Haemodynamic Contrast from Photosensitized Vasculature

Imaging Bioluminescence by Detecting Localized Haemodynamic Contrast from Photosensitized Vasculature

Academic News Report: New MRI Technology Achieves Biological Fluorescence Imaging by Detecting Local Hemodynamics of Photosensitive Blood Vessels Academic Background Introduction Bioluminescent probes are widely used for monitoring biomedical processes and cellular targets in living animals. However, the absorption and scattering of visible light b...

Spatial multi-omics at subcellular resolution via high-throughput in situ pairwise sequencing

Spatial multi-omics at subcellular resolution via high-throughput in situ pairwise sequencing

Spatial Multi-omics High Throughput In Situ Pairwise Sequencing at Subcellular Resolution Research Background and Objectives With the continuous advancement in biomedical research, the application of multi-omics technologies in understanding cell functions and disease mechanisms has gained increasing attention. However, many current in situ sequenc...