The Runx2-NLRP3 Axis Orchestrates Matrix Stiffness-Evoked Vascular Smooth Muscle Cell Inflammation

Chronic Kidney Disease: Runx2-NLRP3 Axis Regulates Matrix Stiffness-Induced Vascular Smooth Muscle Cell Inflammation Academic Background Chronic Kidney Disease (CKD) is a common condition worldwide, leading to high morbidity and mortality rates among patients and significantly increasing the risk of cardiovascular events. Arterial stiffening, chara...

Effects of Algorithmic Transparency on User Experience and Physiological Responses

The Impact of Algorithmic Transparency on User Experience and Physiological Responses Academic Background With the rapid development of Affective Computing technology, Affect-aware Task Adaptation systems have gradually become a research hotspot. These systems recognize users’ psychological states through various measurements (e.g., physiological s...

Phonetically-Anchored Domain Adaptation for Cross-Lingual Speech Emotion Recognition

Phonetic-Anchored Domain Adaptation in Cross-Lingual Speech Emotion Recognition Academic Background Speech Emotion Recognition (SER) has broad application prospects in intelligent agents, social robots, voice assistants, and automated call center systems. With the development of globalization, the demand for cross-lingual SER is increasing. However...

Facial 3D Regional Structural Motion Representation Using Lightweight Point Cloud Networks for Micro-Expression Recognition

3D Regional Structural Motion Representation Using Lightweight Point Cloud Networks for Micro-Expression Recognition Academic Background Micro-expressions (MEs) are brief and subtle facial expressions in human emotional expression, typically lasting between 1⁄25 and 1⁄5 of a second. Due to their spontaneity, rapidity, and difficulty to control, mic...

Experimental Constraints on the Symmetron Field with a Magnetically Levitated Force Sensor

Experimental Constraints on the Symmetron Field: Breakthrough Research with Magnetically Levitated Force Sensors Academic Background Dark energy is the mysterious force behind the accelerated expansion of the universe, but its essence remains an enigma. To explain the nature of dark energy, scientists have proposed various theories, among which the...

Brain Pericytes and Perivascular Fibroblasts Are Stromal Progenitors with Dual Functions in Cerebrovascular Regeneration After Stroke

Dual Functions of Pericytes and Perivascular Fibroblasts in Cerebrovascular Regeneration After Stroke Academic Background Stroke is one of the leading causes of death and disability worldwide. Current therapeutic interventions are mostly limited to acute thrombolytic treatment or thrombectomy, followed by long-term rehabilitation. However, the long...

Latent Circuit Inference from Heterogeneous Neural Responses during Cognitive Tasks

Inferring Latent Neural Circuits from Heterogeneous Neural Responses During Cognitive Tasks Academic Background In cognitive tasks, higher cortical areas of the brain (such as the prefrontal cortex, PFC) are responsible for integrating a variety of sensory, cognitive, and motor signals. However, the responses of individual neurons often exhibit com...

Separating Cognitive and Motor Processes in the Behaving Mouse

Separating Cognitive and Motor Processes: A Breakthrough in Mouse Behavioral Research Academic Background In the study of animal behavior, cognitive processes and motor processes are often closely intertwined. For example, when a mouse explores its environment, its facial expressions or active sampling behaviors not only reflect movement but are al...

The Architecture of the Human Default Mode Network Explored through Cytoarchitecture, Wiring and Signal Flow

Exploration of the Architecture of the Human Default Mode Network: A Study Based on Cytoarchitecture, Wiring, and Signal Flow Academic Background The Default Mode Network (DMN) is a set of brain regions that are highly active during resting states, primarily distributed across the frontal, temporal, and parietal lobes. The DMN plays a crucial role ...

Mapping the Cellular Etiology of Schizophrenia and Complex Brain Phenotypes

Cell-Type Classification of Psychiatric Disorders: New Study Reveals Cellular Basis of Schizophrenia and Other Complex Brain Disorders Academic Background Psychiatric disorders, such as schizophrenia, depression, and bipolar disorder, are significant public health issues worldwide. These disorders are typically caused by a combination of multiple g...