Neural Mechanisms of Visual Perception and Motor Coordination Academic Background In daily life, animals need to distinguish sensory experiences caused by the external environment from those elicited by their own movements. This distinction is crucial for accurate perception and motor control. However, the diversity of behaviors and their complex i...
Retrieval of Conditioned Immune Response in Mice is Mediated by an Anterior-Posterior Insular Circuit Academic Background The bidirectional relationship between the brain and the immune system is a cornerstone of philosophical and scientific research. In recent years, researchers have identified multiple pathways through which the immune system inf...
The Formation of Reliable Representations in Visual Cortex Development Academic Background The development of the visual cortex is a significant area of research in neuroscience. In early development, the network structure of the visual cortex has already formed, but how these networks respond to the onset of visual experience and ultimately form m...
Study on the Propagation of Neuronal Micronuclei Regulating Microglial Characteristics Academic Background Microglia, the resident immune cells in the central nervous system (CNS), play a crucial role in maintaining brain homeostasis, regulating neuronal development, synaptic pruning, and responding to pathological states. However, despite extensiv...
Temporal Dynamics Constraints on Neural Population Activity: Computational Mechanisms of Neural Activity Revealed by Brain-Computer Interfaces Academic Background How neural activity in the brain evolves over time is a central issue in understanding sensory, motor, and cognitive functions. For a long time, network models have posited that the brain...
New Discoveries in Astrocyte Regulation of Behavior: Application of the AstroLight Tool Academic Background For a long time, neuroscience research has primarily focused on neuronal activity, while neglecting the role of astrocytes in brain function. Although astrocytes are one of the most numerous cell types in the brain, they have traditionally be...
NOMPC Ion Channel Hinge Forms Gating Spring to Initiate Mechanosensation Academic Background Mechanosensation is the process by which organisms perceive external mechanical stimuli and convert them into electrical signals. This process plays a crucial role in touch, hearing, gravity perception, and the movement of internal organs and limbs. The ini...
Pathological Link Between Kidney Disease and Parkinson’s Disease Academic Background Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the abnormal aggregation of α-synuclein (α-syn) in the brain, forming Lewy bodies (LBs) and Lewy neurites (LNs). In recent years, increasing evidence suggests that the pathological agg...
Neural Mechanisms and Relational Learning: Rapid Knowledge Reassembly in Neural Networks Background Humans and animals possess a remarkable ability to learn relationships between items in experience (such as stimuli, objects, and events), enabling structured generalization and rapid information assimilation. A fundamental type of such relational le...
Aberrant Splicing in Huntington’s Disease Accompanies Disrupted TDP-43 Activity and Altered m6A RNA Modification Academic Background Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms. The disease is caused by a CAG repeat expansion in the HTT gene, leading to ab...