Quantitative expression of latent disease factors in individuals associated with psychopathology dimensions and treatment response

Quantitative expression of latent disease factors in individuals associated with psychopathology dimensions and treatment response

Study on Quantitative Expression and Treatment Response of Latent Disease Factors Underlying Psychopathological Dimensions Revealed by Unsupervised Machine Learning Research Background Heterogeneity and comorbidity are prevalent in psychiatric diagnoses, posing challenges for precise diagnosis and personalized treatment. For instance, Autism Spectr...

The Neurocomputational Mechanism Underlying Decision-Making on Unfairness to Self and Others

Neural computational mechanisms underlying fairness-based decisions: Self-Unfairness and Other-Unfairness Abstract: Fairness is a fundamental value in human society, and individuals show concern for both self-unfairness and other-unfairness. However, there has been a long-standing debate on whether self-unfairness and other-unfairness evoke shared ...

Distinct Contributions of Alpha and Beta Oscillations to Context-Dependent Visual Size Perception

Revealing Different Cognitive Mechanisms of the Ebbinghaus Illusion Through Neural Oscillations Academic Background Human perception of size in vision is not entirely faithful to the physical world and is highly dependent on context. For example, when an object is surrounded by several smaller objects, it appears larger than when surrounded by larg...

Dentate Gyrus Morphogenesis is Regulated by an Autism Risk Gene Trio Function in Granule Cells

Research Background and Objectives Autism Spectrum Disorders (ASDs) are a group of highly heritable neurodevelopmental disorders, primarily characterized by abnormal social interactions, communication deficits, and restricted repetitive behaviors or interests. Previous studies have reported structural changes in brain regions including the hippocam...

Repetitive Administration of Low-Dose Lipopolysaccharide Improves Repeated Social Defeat Stress-Induced Behavioral Abnormalities and Aberrant Immune Response

Repeated Low-Dose Lipopolysaccharide Pretreatment Improves Behavioral Abnormalities and Aberrant Immune Responses Induced by Repeated Social Defeat Stress Background Stress significantly impacts human health, with chronic stress particularly inducing various physiological and psychological disorders. The hypothalamic-pituitary-adrenal (HPA) axis is...

A Measure of Reliability Convergence to Select and Optimize Cognitive Tasks for Individual Differences Research

Academic Report Research Background In recent years, there has been growing interest in individual differences within the fields of psychology and cognitive neuroscience. However, many studies face a replication crisis, particularly evident in research exploring brain-behavior correlations. A key element for replicable individual differences resear...

Humans Need Auditory Experience to Produce Typical Volitional Nonverbal Vocalizations

Humans Need Auditory Experience to Produce Typical Volitional Nonverbal Vocalizations Introduction This research paper explores whether humans require auditory input to produce nonverbal emotional expressions (such as screams and cries). While these nonverbal vocalizations seem to have a strong reflexive basis, many emotional vocalizations are unde...

Longitudinal Associations Between Time Perspective and Life Satisfaction Across Adulthood

Research Report on the Long-term Relationship between Time Perspective and Life Satisfaction in Adulthood Research Background Time perspective is an important predictor of human well-being. However, time perspective itself changes with development. A future-dominated time perspective gradually gives way to a present and past-focused perspective as ...

Anchor Objects Drive Realism While Diagnostic Objects Drive Categorization in GAN Generated Scenes

Anchor Objects Drive Realism While Diagnostic Objects Drive Categorization in GAN Generated Scenes

Background Introduction In the human visual system, the understanding and navigation of natural scenes are exceptionally outstanding in terms of both complexity and efficiency. This process requires the transformation of incoming sensory information into visual features ranging from low-level to high-level, such as edges, object parts, and objects ...

The Mediating Role of Systemic Inflammation and Moderating Role of Racialization in Disparities in Incident Dementia

The Mediating Role of Systemic Inflammation in the Differences in Cognitive Disease Incidence and the Moderating Role of Racialization This study examines the link between systemic racism and the increased burden of cognitive disease. Researchers investigated the mediating role of C-reactive protein (CRP) as a marker of systemic inflammation in the...