Physical Exercise Inhibits Cognitive Impairment and Memory Loss in Aged Mice, and Enhances Pre- and Post-Synaptic Proteins in the Hippocampus of Young and Aged Mice

A scientific paper authored by Ricardo Augusto Leoni de Sousa and his research team was published in Volume 26, Issue 31 of the journal “Neuromolecular Medicine” in 2024. The paper is titled “Physical exercise inhibits cognitive impairment and memory loss in aged mice, and enhances pre- and post-synaptic proteins in the hippocampus of young and age...

Customized Passive-Dynamic Ankle–Foot Orthoses Can Improve Walking Economy and Speed for Many Individuals Post-Stroke

Custom Passive Dynamic Ankle-Foot Orthoses Can Improve Walking Economy and Speed Post-Stroke Background Introduction Stroke is one of the leading causes of long-term disability, affecting over 795,000 individuals annually in the United States. A common post-stroke issue is plantar flexor weakness in the affected limb, impacting the ability to contr...

Automatic Gait Events Detection with Inertial Measurement Units: Healthy Subjects and Moderate to Severe Impaired Patients

A New Method for Automatic Gait Event Detection: Analysis of Inertial Measurement Units in Healthy Subjects and Patients with Moderate to Severe Impairment Cyril Voisard, Nicolas de L’Escalopier, Damien Ricard, Laurent Oudre. Journal of NeuroEngineering and Rehabilitation (2024) 21:104 https://doi.org/10.1186/s12984-024-01405-x Background of the St...

Study on the Effects of Transcutaneous Spinal Cord Stimulation on Bimanual Coordination

Coordination of Both Hands and Spinal Cord Neuroregulation: How Transcutaneous Spinal Cord Stimulation Changes the Neural Substrate of Bimanual Actions Background: Humans use their arms in complex ways, often requiring coordination of both hands. Neurological disorders have limited this distinctive feature of the human motor system. Understanding h...

Wearable Biofeedback Device to Assess Gait Features and Improve Gait Pattern in People with Parkinson’s Disease: A Case Series

Wearable Biofeedback Device to Assess Gait Features and Improve Gait Pattern in People with Parkinson’s Disease: A Case Series

Application of Wearable Biofeedback Device in Gait Assessment for Parkinson’s Disease Patients: A Case Series Study Research Background Patients with Parkinson’s Disease (PD) often exhibit abnormal gait patterns, severely affecting their independence and quality of life. Gait abnormalities primarily manifest as reduced stride length, increased step...

Differential Training Benefits and Motor Unit Remodeling in Wrist Force Precision Tasks Following High and Low Load Blood Flow Restriction Exercises Under Volume-Matched Conditions

Differential Training Benefits and Motor Unit Remodeling in Wrist Force Precision Tasks Following High and Low Load Blood Flow Restriction Exercises Under Volume-Matched Conditions

Study on the Differential Effects of Blood Flow Restriction Training on Strength Gains and Precise Force Control Research Background Blood Flow Restriction (BFR) training, an emerging method for enhancing muscle strength, has garnered attention from researchers and clinical medicine in recent years. BFR training with low-load resistance exercise en...

A Conserved Complex Lipid Signature Marks Human Muscle Aging and Responds to Short-Term Exercise

Study on Human Muscle Aging Reveals Impact of Short-term Exercise on Lipid Composition Research Background As the global population ages, understanding the physiological changes associated with aging has become a key focus in scientific research. Previous studies using animal models have indicated that complex lipids, such as phospholipids, play im...

Effects of a Combined Exercise and Dietary Intervention on Body Composition, Physical Functioning, and Fatigue in Patients with Ovarian Cancer: Results of the Padova Trial

Effects of a Combined Exercise and Dietary Intervention on Body Composition, Physical Functioning, and Fatigue in Patients with Ovarian Cancer: Results of the Padova Trial

Effects of Combined Exercise and Dietary Intervention on Body Composition, Physical Functioning, and Fatigue in Ovarian Cancer Patients: PADOVA Trial Results Academic Background Ovarian cancer is the seventh most common cancer among women, usually detected at an advanced stage, with an overall 5-year survival rate as low as 30-40%. Standard ovarian...

Decision Uncertainty as a Context for Motor Memory

Decision Uncertainty as a Contextual Cue for Motor Memory Background In a penalty shootout during a soccer match, players may face two distinctly different decision-making scenarios. For example, a player may decisively kick the ball to the right corner after seeing the goalkeeper move to the other side, or he may kick the same way without being ce...

Time of Exercise Differentially Impacts Bone Growth in Mice

Differential Effects of Exercise Timing on Skeletal Growth in Mice Introduction Skeletal growth is crucial for adult height and bone health. Studies have shown that exercise can effectively increase bone density, but the optimal exercise timing remains unclear. This study aimed to investigate the optimal exercise timing by comparing the effects of ...